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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGFR1OP
All Species:
24.85
Human Site:
S348
Identified Species:
45.56
UniProt:
O95684
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95684
NP_008976.1
399
43065
S348
F
N
S
T
S
H
R
S
E
K
S
E
I
S
I
Chimpanzee
Pan troglodytes
XP_527596
399
43086
S348
F
N
S
T
S
H
R
S
E
K
S
E
I
S
I
Rhesus Macaque
Macaca mulatta
XP_001102430
399
42988
S348
F
N
S
T
S
H
R
S
E
K
S
E
I
S
I
Dog
Lupus familis
XP_855273
374
40330
S323
F
N
S
T
S
H
R
S
E
K
S
E
L
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q66JX5
399
42740
S348
F
N
S
A
S
H
R
S
E
K
S
E
L
S
I
Rat
Rattus norvegicus
Q4V7C1
399
42993
S348
F
N
S
A
S
H
R
S
E
K
S
E
L
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509359
156
16754
T106
N
K
H
V
G
S
L
T
S
L
S
N
A
P
P
Chicken
Gallus gallus
Q5ZJ24
175
19811
S125
G
K
E
E
S
T
Q
S
T
L
P
K
V
S
L
Frog
Xenopus laevis
NP_001089813
440
50470
R389
D
F
N
S
T
S
Q
R
S
D
K
S
D
V
S
Zebra Danio
Brachydanio rerio
NP_001002125
511
56229
R460
D
D
D
F
N
S
H
R
S
E
N
S
K
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396617
469
52538
K413
S
P
K
L
Q
T
K
K
Q
D
K
I
H
S
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002311121
263
29325
R213
R
K
D
D
N
S
W
R
Y
D
G
D
E
L
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567013
257
29167
N207
G
Y
R
K
D
E
S
N
W
R
Y
D
T
E
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98.2
81.4
N.A.
84.7
86.9
N.A.
27.5
23.3
42
41.6
N.A.
N.A.
28.1
N.A.
N.A.
Protein Similarity:
100
99
99
86.7
N.A.
90.9
92.7
N.A.
32.8
31.3
57.2
53.4
N.A.
N.A.
46.7
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
6.6
20
0
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
13.3
46.6
26.6
33.3
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
21.5
N.A.
N.A.
21.8
N.A.
N.A.
Protein Similarity:
36.8
N.A.
N.A.
35.8
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
0
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
8
16
8
8
0
0
0
0
24
0
16
8
0
8
% D
% Glu:
0
0
8
8
0
8
0
0
47
8
0
47
8
8
8
% E
% Phe:
47
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
16
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
8
0
0
47
8
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
8
24
0
47
% I
% Lys:
0
24
8
8
0
0
8
8
0
47
16
8
8
0
0
% K
% Leu:
0
0
0
8
0
0
8
0
0
16
0
0
24
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
47
8
0
16
0
0
8
0
0
8
8
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
8
0
0
8
16
% P
% Gln:
0
0
0
0
8
0
16
0
8
0
0
0
0
0
0
% Q
% Arg:
8
0
8
0
0
0
47
24
0
8
0
0
0
0
0
% R
% Ser:
8
0
47
8
54
31
8
54
24
0
54
16
0
70
8
% S
% Thr:
0
0
0
31
8
16
0
8
8
0
0
0
8
0
0
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
0
8
8
8
% V
% Trp:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
8
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _