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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP1R3D
All Species:
14.55
Human Site:
S25
Identified Species:
32
UniProt:
O95685
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95685
NP_006233.1
299
32559
S25
K
L
G
P
R
S
L
S
C
L
S
D
L
D
G
Chimpanzee
Pan troglodytes
XP_001142110
299
32561
S25
K
L
G
P
R
S
L
S
C
L
S
D
L
D
G
Rhesus Macaque
Macaca mulatta
XP_001090753
299
32739
S25
K
L
T
P
R
S
L
S
C
L
S
D
L
D
G
Dog
Lupus familis
XP_543078
299
32255
S25
K
P
A
P
R
S
L
S
C
V
S
D
L
D
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRJ4
279
30556
Y27
A
L
T
E
R
A
Y
Y
R
S
Q
R
P
S
L
Rat
Rattus norvegicus
P0C7L8
279
30605
Y27
A
L
T
E
R
A
Y
Y
R
S
Q
R
P
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511700
305
33609
R28
P
V
P
R
A
A
P
R
S
L
S
C
L
A
E
Chicken
Gallus gallus
XP_417397
303
34691
Q32
G
A
P
G
Q
G
Q
Q
Q
P
S
V
V
R
P
Frog
Xenopus laevis
NP_001084656
223
25129
Zebra Danio
Brachydanio rerio
Q6P950
317
36305
L30
D
V
A
M
R
I
C
L
A
H
S
P
P
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783512
425
46821
N86
E
G
I
E
D
W
I
N
S
G
T
P
T
N
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
96.3
86.9
N.A.
36.1
35.4
N.A.
63.9
54.7
26.4
28.7
N.A.
N.A.
N.A.
N.A.
22.8
Protein Similarity:
100
99.3
97.3
90.9
N.A.
48.4
48.8
N.A.
73.1
64
41.1
43.5
N.A.
N.A.
N.A.
N.A.
35.5
P-Site Identity:
100
100
93.3
80
N.A.
13.3
13.3
N.A.
20
6.6
0
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
86.6
N.A.
20
20
N.A.
33.3
20
0
20
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
19
0
10
28
0
0
10
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
10
0
37
0
0
10
0
0
0
% C
% Asp:
10
0
0
0
10
0
0
0
0
0
0
37
0
37
0
% D
% Glu:
10
0
0
28
0
0
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
19
10
0
10
0
0
0
10
0
0
0
0
46
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
10
10
0
0
0
0
0
0
0
0
% I
% Lys:
37
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
46
0
0
0
0
37
10
0
37
0
0
46
10
19
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% N
% Pro:
10
10
19
37
0
0
10
0
0
10
0
19
28
0
10
% P
% Gln:
0
0
0
0
10
0
10
10
10
0
19
0
0
0
0
% Q
% Arg:
0
0
0
10
64
0
0
10
19
0
0
19
0
10
10
% R
% Ser:
0
0
0
0
0
37
0
37
19
19
64
0
0
19
0
% S
% Thr:
0
0
28
0
0
0
0
0
0
0
10
0
10
0
0
% T
% Val:
0
19
0
0
0
0
0
0
0
10
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
19
19
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _