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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPP1R3D All Species: 18.48
Human Site: Y208 Identified Species: 40.67
UniProt: O95685 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95685 NP_006233.1 299 32559 Y208 E K Q V A V R Y T F S G W R S
Chimpanzee Pan troglodytes XP_001142110 299 32561 Y208 E K Q V A V R Y T F S G W R S
Rhesus Macaque Macaca mulatta XP_001090753 299 32739 Y208 E K Q V A V R Y T F S G W R S
Dog Lupus familis XP_543078 299 32255 Y208 E K Q V A V R Y T F S D W R S
Cat Felis silvestris
Mouse Mus musculus Q8BRJ4 279 30556 R188 L D L A Y E K R V S V R W S A
Rat Rattus norvegicus P0C7L8 279 30605 R188 L D L A Y E K R V S V R W S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511700 305 33609 R216 F E K Q V S V R Y T F N R W R
Chicken Gallus gallus XP_417397 303 34691 Y210 E K Q V S V R Y T F N Q W K S
Frog Xenopus laevis NP_001084656 223 25129 Y135 V R V R N I G Y E K R V T L R
Zebra Danio Brachydanio rerio Q6P950 317 36305 I189 E K V V H V R I T F D S W K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783512 425 46821 M275 D P C P S P P M T V L A F E S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 96.3 86.9 N.A. 36.1 35.4 N.A. 63.9 54.7 26.4 28.7 N.A. N.A. N.A. N.A. 22.8
Protein Similarity: 100 99.3 97.3 90.9 N.A. 48.4 48.8 N.A. 73.1 64 41.1 43.5 N.A. N.A. N.A. N.A. 35.5
P-Site Identity: 100 100 100 93.3 N.A. 6.6 6.6 N.A. 0 73.3 6.6 60 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 93.3 N.A. 20 20 N.A. 13.3 93.3 20 66.6 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 19 37 0 0 0 0 0 0 10 0 0 19 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 19 0 0 0 0 0 0 0 0 10 10 0 0 0 % D
% Glu: 55 10 0 0 0 19 0 0 10 0 0 0 0 10 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 55 10 0 10 0 0 % F
% Gly: 0 0 0 0 0 0 10 0 0 0 0 28 0 0 0 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % I
% Lys: 0 55 10 0 0 0 19 0 0 10 0 0 0 19 0 % K
% Leu: 19 0 19 0 0 0 0 0 0 0 10 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 10 10 0 0 0 % N
% Pro: 0 10 0 10 0 10 10 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 46 10 0 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 0 10 0 10 0 0 55 28 0 0 10 19 10 37 19 % R
% Ser: 0 0 0 0 19 10 0 0 0 19 37 10 0 19 64 % S
% Thr: 0 0 0 0 0 0 0 0 64 10 0 0 10 0 0 % T
% Val: 10 0 19 55 10 55 10 0 19 10 19 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 73 10 0 % W
% Tyr: 0 0 0 0 19 0 0 55 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _