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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP1R3D
All Species:
28.18
Human Site:
Y275
Identified Species:
62
UniProt:
O95685
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95685
NP_006233.1
299
32559
Y275
D
N
N
D
H
R
D
Y
S
L
T
C
R
N
H
Chimpanzee
Pan troglodytes
XP_001142110
299
32561
Y275
D
N
N
D
H
R
D
Y
S
L
T
C
R
N
H
Rhesus Macaque
Macaca mulatta
XP_001090753
299
32739
Y275
D
N
N
D
C
R
D
Y
S
L
T
C
R
N
H
Dog
Lupus familis
XP_543078
299
32255
Y275
D
N
N
H
G
R
D
Y
S
L
T
C
R
N
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRJ4
279
30556
Y256
D
N
N
G
G
R
D
Y
A
L
L
G
P
E
H
Rat
Rattus norvegicus
P0C7L8
279
30605
Y256
D
N
N
G
G
R
D
Y
A
L
L
G
P
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511700
305
33609
Y282
D
N
N
G
G
R
D
Y
S
L
V
C
R
S
H
Chicken
Gallus gallus
XP_417397
303
34691
Y280
D
N
N
R
G
K
N
Y
S
L
T
C
R
T
H
Frog
Xenopus laevis
NP_001084656
223
25129
H201
G
E
E
Y
W
D
N
H
D
G
K
N
Y
A
L
Zebra Danio
Brachydanio rerio
Q6P950
317
36305
Y255
D
N
N
D
G
K
N
Y
K
L
V
H
T
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783512
425
46821
A353
W
D
N
W
T
T
H
A
N
I
M
A
R
Y
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
96.3
86.9
N.A.
36.1
35.4
N.A.
63.9
54.7
26.4
28.7
N.A.
N.A.
N.A.
N.A.
22.8
Protein Similarity:
100
99.3
97.3
90.9
N.A.
48.4
48.8
N.A.
73.1
64
41.1
43.5
N.A.
N.A.
N.A.
N.A.
35.5
P-Site Identity:
100
100
93.3
86.6
N.A.
53.3
53.3
N.A.
73.3
66.6
0
40
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
86.6
N.A.
60
60
N.A.
80
80
13.3
60
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
19
0
0
10
0
10
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
55
0
0
0
% C
% Asp:
82
10
0
37
0
10
64
0
10
0
0
0
0
0
0
% D
% Glu:
0
10
10
0
0
0
0
0
0
0
0
0
0
28
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
28
55
0
0
0
0
10
0
19
0
0
0
% G
% His:
0
0
0
10
19
0
10
10
0
0
0
10
0
0
73
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
19
0
0
10
0
10
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
82
19
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
82
91
0
0
0
28
0
10
0
0
10
0
37
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
64
0
0
0
0
0
0
64
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
55
0
0
0
0
10
0
% S
% Thr:
0
0
0
0
10
10
0
0
0
0
46
0
10
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
10
% V
% Trp:
10
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
82
0
0
0
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _