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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POP4 All Species: 10.3
Human Site: S17 Identified Species: 18.89
UniProt: O95707 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95707 NP_006618.1 220 25425 S17 S Q K E A N D S D V Q P S G A
Chimpanzee Pan troglodytes XP_512983 220 25433 S17 S Q K E A N D S D V Q P S G A
Rhesus Macaque Macaca mulatta XP_001084400 221 25519 S17 S Q K E A K D S D V Q P P G A
Dog Lupus familis XP_855541 307 34059 L104 S Q K E A K E L E V Q L P G A
Cat Felis silvestris
Mouse Mus musculus Q9CR08 221 25618 H17 S H K E A K D H D V Q E L G S
Rat Rattus norvegicus Q5M882 221 25614 H17 S H K E A K D H D V Q E L G T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507028 152 17315
Chicken Gallus gallus NP_001139386 220 25566 L17 P R E A A K E L R L Q P Q G S
Frog Xenopus laevis NP_001086097 223 25896 L21 P P D E A R Q L G L E L Q E P
Zebra Danio Brachydanio rerio NP_001018585 219 24945 L17 P S D Q S H L L G V E S Q H G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648168 206 23900 I17 E F I S D L V I P H Q R C N V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784253 279 32400 S46 N P Q K F I S S F M K R H T P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38336 279 32863 P20 F T K C L E D P E K P F N E N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 96.3 61.8 N.A. 82.3 84.6 N.A. 57.7 69 65.9 63.6 N.A. 30.9 N.A. N.A. 35.8
Protein Similarity: 100 100 97.2 67 N.A. 90.5 90 N.A. 65.4 85.4 82 78.1 N.A. 50.9 N.A. N.A. 53
P-Site Identity: 100 100 86.6 60 N.A. 60 60 N.A. 0 26.6 13.3 6.6 N.A. 6.6 N.A. N.A. 6.6
P-Site Similarity: 100 100 86.6 73.3 N.A. 66.6 60 N.A. 0 60 26.6 33.3 N.A. 6.6 N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 62 0 0 0 0 0 0 0 0 0 31 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 16 0 8 0 47 0 39 0 0 0 0 0 0 % D
% Glu: 8 0 8 54 0 8 16 0 16 0 16 16 0 16 0 % E
% Phe: 8 8 0 0 8 0 0 0 8 0 0 8 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 16 0 0 0 0 54 8 % G
% His: 0 16 0 0 0 8 0 16 0 8 0 0 8 8 0 % H
% Ile: 0 0 8 0 0 8 0 8 0 0 0 0 0 0 0 % I
% Lys: 0 0 54 8 0 39 0 0 0 8 8 0 0 0 0 % K
% Leu: 0 0 0 0 8 8 8 31 0 16 0 16 16 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 16 0 0 0 0 0 0 8 8 8 % N
% Pro: 24 16 0 0 0 0 0 8 8 0 8 31 16 0 16 % P
% Gln: 0 31 8 8 0 0 8 0 0 0 62 0 24 0 0 % Q
% Arg: 0 8 0 0 0 8 0 0 8 0 0 16 0 0 0 % R
% Ser: 47 8 0 8 8 0 8 31 0 0 0 8 16 0 16 % S
% Thr: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 8 % T
% Val: 0 0 0 0 0 0 8 0 0 54 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _