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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POP4 All Species: 40.3
Human Site: Y109 Identified Species: 73.89
UniProt: O95707 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95707 NP_006618.1 220 25425 Y109 L H E L W K Q Y I R D L C S G
Chimpanzee Pan troglodytes XP_512983 220 25433 Y109 L H E L W K Q Y I R D L C N G
Rhesus Macaque Macaca mulatta XP_001084400 221 25519 Y110 L H E L W K Q Y I K D L C N G
Dog Lupus familis XP_855541 307 34059 Y196 L H E L W K Q Y I R D L C G G
Cat Felis silvestris
Mouse Mus musculus Q9CR08 221 25618 Y110 L H E L W K Q Y I R D L C N G
Rat Rattus norvegicus Q5M882 221 25614 Y110 L H E L W K Q Y I R D L C N G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507028 152 17315 G48 Y I R D L C N G L R P D T Q P
Chicken Gallus gallus NP_001139386 220 25566 Y109 L H E L W K Q Y I R D L C Y G
Frog Xenopus laevis NP_001086097 223 25896 Y112 L H E L W T Q Y I R D L C N G
Zebra Danio Brachydanio rerio NP_001018585 219 24945 Y108 L H E L W K S Y I E D L C N G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648168 206 23900 P102 L R E G D E V P Q V H D A R Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784253 279 32400 Y138 L H Q L W L D Y M R E A V L A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38336 279 32863 Y150 Y K E L W I N Y I K E L L N I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 96.3 61.8 N.A. 82.3 84.6 N.A. 57.7 69 65.9 63.6 N.A. 30.9 N.A. N.A. 35.8
Protein Similarity: 100 100 97.2 67 N.A. 90.5 90 N.A. 65.4 85.4 82 78.1 N.A. 50.9 N.A. N.A. 53
P-Site Identity: 100 93.3 86.6 93.3 N.A. 93.3 93.3 N.A. 6.6 93.3 86.6 80 N.A. 13.3 N.A. N.A. 40
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. 13.3 93.3 93.3 86.6 N.A. 20 N.A. N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 40 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 8 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 70 0 0 % C
% Asp: 0 0 0 8 8 0 8 0 0 0 70 16 0 0 0 % D
% Glu: 0 0 85 0 0 8 0 0 0 8 16 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 0 0 0 8 0 0 0 0 0 8 70 % G
% His: 0 77 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 8 0 0 0 8 0 0 77 0 0 0 0 0 8 % I
% Lys: 0 8 0 0 0 62 0 0 0 16 0 0 0 0 0 % K
% Leu: 85 0 0 85 8 8 0 0 8 0 0 77 8 8 0 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 16 0 0 0 0 0 0 54 0 % N
% Pro: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 8 % P
% Gln: 0 0 8 0 0 0 62 0 8 0 0 0 0 8 0 % Q
% Arg: 0 8 8 0 0 0 0 0 0 70 0 0 0 8 0 % R
% Ser: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 0 % S
% Thr: 0 0 0 0 0 8 0 0 0 0 0 0 8 0 0 % T
% Val: 0 0 0 0 0 0 8 0 0 8 0 0 8 0 0 % V
% Trp: 0 0 0 0 85 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 16 0 0 0 0 0 0 85 0 0 0 0 0 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _