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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HERC2
All Species:
22.73
Human Site:
S1366
Identified Species:
55.56
UniProt:
O95714
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95714
NP_004658.3
4834
527472
S1366
K
D
E
D
H
C
S
S
P
G
G
T
P
A
S
Chimpanzee
Pan troglodytes
XP_001174017
4861
532381
E1378
E
E
E
E
R
E
H
E
V
M
T
A
G
K
I
Rhesus Macaque
Macaca mulatta
XP_001109429
4819
524760
S1366
K
D
E
D
H
C
S
S
P
G
G
T
P
A
S
Dog
Lupus familis
XP_536160
4837
527375
S1367
K
D
E
D
H
C
S
S
P
G
G
T
P
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q4U2R1
4836
527512
S1367
K
D
E
D
H
C
S
S
P
G
G
T
P
I
S
Rat
Rattus norvegicus
NP_001100990
4779
521102
S1310
K
D
E
D
H
C
S
S
P
G
G
T
P
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233308
4839
528969
S1367
K
D
E
D
H
C
S
S
P
G
N
T
T
P
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686789
1443
155036
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VR91
4912
529978
H1447
K
G
E
A
R
S
S
H
S
C
H
S
T
A
G
Honey Bee
Apis mellifera
XP_395007
4791
531039
T1354
K
G
E
A
R
S
N
T
S
T
A
A
N
S
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
23.1
98.1
96.5
N.A.
95.3
94.4
N.A.
N.A.
91.3
N.A.
27
N.A.
43.7
49.2
N.A.
N.A.
Protein Similarity:
100
40.3
98.6
98
N.A.
97.5
96.6
N.A.
N.A.
95.9
N.A.
28.6
N.A.
60
66.7
N.A.
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
93.3
93.3
N.A.
N.A.
73.3
N.A.
0
N.A.
26.6
13.3
N.A.
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
93.3
93.3
N.A.
N.A.
80
N.A.
0
N.A.
33.3
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
0
0
0
0
0
0
10
20
0
40
0
% A
% Cys:
0
0
0
0
0
60
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
60
0
60
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
10
90
10
0
10
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
20
0
0
0
0
0
0
0
60
50
0
10
0
10
% G
% His:
0
0
0
0
60
0
10
10
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
10
% I
% Lys:
80
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
10
0
10
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
60
0
0
0
50
10
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
30
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
20
70
60
20
0
0
10
0
10
50
% S
% Thr:
0
0
0
0
0
0
0
10
0
10
10
60
20
0
0
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _