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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESRRB
All Species:
9.39
Human Site:
Y356
Identified Species:
22.96
UniProt:
O95718
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95718
NP_004443
500
55619
Y356
L
A
N
S
D
S
M
Y
I
E
D
L
E
A
V
Chimpanzee
Pan troglodytes
XP_001162740
515
56733
Y356
L
A
N
S
D
S
M
Y
I
E
D
L
E
A
V
Rhesus Macaque
Macaca mulatta
XP_001100608
454
50089
S333
Y
I
M
D
E
E
H
S
R
L
A
G
L
L
E
Dog
Lupus familis
XP_547920
454
50335
S333
Y
I
M
D
E
E
H
S
R
L
A
G
L
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61539
433
48383
G316
E
E
H
S
R
L
V
G
L
L
D
L
Y
R
A
Rat
Rattus norvegicus
P11475
433
48269
G316
E
E
H
S
R
L
V
G
L
L
E
L
Y
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510517
462
51532
Y334
E
L
V
Y
A
E
D
Y
I
M
D
E
D
Q
S
Chicken
Gallus gallus
P06212
589
66728
Y453
I
L
L
N
S
G
V
Y
T
F
L
S
S
T
L
Frog
Xenopus laevis
P81559
586
66062
Y451
I
L
L
N
S
G
V
Y
T
F
L
S
S
T
L
Zebra Danio
Brachydanio rerio
P57717
569
62828
F427
I
L
I
N
S
G
A
F
S
F
C
S
S
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.6
81.8
85.4
N.A.
80.4
82.8
N.A.
68.4
32
30.8
30.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
86.9
83.4
85.8
N.A.
82.8
84.4
N.A.
77.8
50.5
48.6
49.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
0
N.A.
20
13.3
N.A.
20
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
6.6
N.A.
40
40
N.A.
26.6
33.3
33.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
0
10
0
10
0
0
0
20
0
0
20
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
20
20
0
10
0
0
0
40
0
10
0
0
% D
% Glu:
30
20
0
0
20
30
0
0
0
20
10
10
20
0
20
% E
% Phe:
0
0
0
0
0
0
0
10
0
30
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
30
0
20
0
0
0
20
0
0
0
% G
% His:
0
0
20
0
0
0
20
0
0
0
0
0
0
0
0
% H
% Ile:
30
20
10
0
0
0
0
0
30
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
20
40
20
0
0
20
0
0
20
40
20
40
20
20
20
% L
% Met:
0
0
20
0
0
0
20
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
20
30
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
20
0
0
0
20
0
0
0
0
20
0
% R
% Ser:
0
0
0
40
30
20
0
20
10
0
0
30
30
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
20
0
0
0
0
20
0
% T
% Val:
0
0
10
0
0
0
40
0
0
0
0
0
0
0
30
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
20
0
0
10
0
0
0
50
0
0
0
0
20
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _