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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SNAP29
All Species:
16.36
Human Site:
S250
Identified Species:
27.69
UniProt:
O95721
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95721
NP_004773.1
258
28970
S250
K
L
D
V
N
I
K
S
T
E
R
K
V
R
Q
Chimpanzee
Pan troglodytes
XP_514997
258
28925
S250
K
L
D
V
N
I
K
S
T
E
R
K
V
R
Q
Rhesus Macaque
Macaca mulatta
XP_001086227
258
28905
S250
K
L
D
V
N
I
K
S
T
E
R
K
V
R
Q
Dog
Lupus familis
XP_543568
258
28807
S250
K
L
D
V
N
I
K
S
T
E
R
K
V
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERB0
260
29553
I250
V
D
K
L
D
V
N
I
K
S
T
E
K
K
V
Rat
Rattus norvegicus
Q9Z2P6
257
29052
T250
L
D
V
N
I
K
S
T
E
K
K
V
R
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517249
178
19208
L171
G
G
L
V
G
E
G
L
S
E
E
T
G
P
R
Chicken
Gallus gallus
NP_001025823
248
28115
I238
V
E
I
L
D
V
G
I
K
S
T
D
K
K
I
Frog
Xenopus laevis
NP_001080076
257
29474
A248
K
M
D
L
N
I
K
A
T
D
K
R
I
R
E
Zebra Danio
Brachydanio rerio
XP_700124
266
29804
K254
K
A
D
T
M
D
G
K
I
S
S
T
N
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523831
284
31577
N275
D
L
K
I
H
K
Q
N
K
D
M
S
K
L
L
Honey Bee
Apis mellifera
XP_624421
262
29666
K251
K
T
D
I
M
L
Q
K
Q
N
K
D
L
T
H
Nematode Worm
Caenorhab. elegans
P83351
277
31097
T244
Q
M
Q
K
I
L
G
T
G
A
S
T
S
Q
T
Sea Urchin
Strong. purpuratus
XP_782713
199
21830
E192
K
L
G
Q
T
D
K
E
V
K
K
I
L
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.2
87.5
N.A.
83
81.7
N.A.
39.5
62
55.8
51.1
N.A.
28.5
33.5
27.4
20.5
Protein Similarity:
100
100
98
92.2
N.A.
90
89.1
N.A.
52.3
79.4
75.9
71
N.A.
46.8
56.4
48.3
42.6
P-Site Identity:
100
100
100
100
N.A.
0
0
N.A.
13.3
0
46.6
26.6
N.A.
6.6
13.3
0
26.6
P-Site Similarity:
100
100
100
100
N.A.
33.3
26.6
N.A.
26.6
26.6
100
26.6
N.A.
40
46.6
33.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
8
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
15
50
0
15
15
0
0
0
15
0
15
0
0
0
% D
% Glu:
0
8
0
0
0
8
0
8
8
36
8
8
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
8
0
8
0
29
0
8
0
0
0
8
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
8
15
15
36
0
15
8
0
0
8
8
0
8
% I
% Lys:
58
0
15
8
0
15
43
15
22
15
29
29
22
15
0
% K
% Leu:
8
43
8
22
0
15
0
8
0
0
0
0
15
8
15
% L
% Met:
0
15
0
0
15
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
8
36
0
8
8
0
8
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
8
0
8
8
0
0
15
0
8
0
0
0
0
15
36
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
29
8
8
50
15
% R
% Ser:
0
0
0
0
0
0
8
29
8
22
15
8
8
0
0
% S
% Thr:
0
8
0
8
8
0
0
15
36
0
15
22
0
8
8
% T
% Val:
15
0
8
36
0
15
0
0
8
0
0
8
29
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _