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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CPNE6 All Species: 23.64
Human Site: S325 Identified Species: 47.27
UniProt: O95741 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95741 NP_006023.1 557 61991 S325 G D P R S S Q S L H C L S P R
Chimpanzee Pan troglodytes XP_516753 575 64376 Y347 R N S C S L H Y I H P Y Q P N
Rhesus Macaque Macaca mulatta XP_001103904 2117 230755 S1885 G D P R S S Q S L H C L S P R
Dog Lupus familis XP_850337 557 61656 S325 G D P R S S Q S L H C L S P R
Cat Felis silvestris
Mouse Mus musculus Q9Z140 557 61762 S325 G D P R S S Q S L H C L S P R
Rat Rattus norvegicus Q5BJS7 553 61792 Y321 L Q P T S L H Y M S P Y Q L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514223 604 68134 Y329 R N S C S L H Y I H P Y Q P N
Chicken Gallus gallus XP_418786 556 62344 Y329 R N S C S L H Y I H P Y Q P N
Frog Xenopus laevis NP_001088611 533 59322 V319 H Y I S P N G V N E Y L T A I
Zebra Danio Brachydanio rerio XP_692981 559 62595 Y329 R N S C S L H Y I N P Y Q P N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XUB9 634 71083 S357 G P P K S S S S L H F M S A D
Sea Urchin Strong. purpuratus XP_789003 539 60320 F320 N E E S S L H F I N L E S P N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60 26.1 98.1 N.A. 97.8 47.5 N.A. 55.2 60.8 50.2 63.8 N.A. N.A. N.A. 35.6 50.8
Protein Similarity: 100 77 26.2 98.7 N.A. 98.7 64 N.A. 71.5 78.4 65.8 78.1 N.A. N.A. N.A. 49.6 68.2
P-Site Identity: 100 20 100 100 N.A. 100 13.3 N.A. 20 20 6.6 13.3 N.A. N.A. N.A. 53.3 20
P-Site Similarity: 100 33.3 100 100 N.A. 100 20 N.A. 33.3 33.3 20 33.3 N.A. N.A. N.A. 66.6 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % A
% Cys: 0 0 0 34 0 0 0 0 0 0 34 0 0 0 0 % C
% Asp: 0 34 0 0 0 0 0 0 0 0 0 0 0 0 9 % D
% Glu: 0 9 9 0 0 0 0 0 0 9 0 9 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 9 0 0 9 0 0 0 0 % F
% Gly: 42 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % G
% His: 9 0 0 0 0 0 50 0 0 67 0 0 0 0 0 % H
% Ile: 0 0 9 0 0 0 0 0 42 0 0 0 0 0 9 % I
% Lys: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 9 0 0 0 0 50 0 0 42 0 9 42 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 0 % M
% Asn: 9 34 0 0 0 9 0 0 9 17 0 0 0 0 42 % N
% Pro: 0 9 50 0 9 0 0 0 0 0 42 0 0 75 0 % P
% Gln: 0 9 0 0 0 0 34 0 0 0 0 0 42 0 0 % Q
% Arg: 34 0 0 34 0 0 0 0 0 0 0 0 0 0 34 % R
% Ser: 0 0 34 17 92 42 9 42 0 9 0 0 50 0 9 % S
% Thr: 0 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % T
% Val: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 42 0 0 9 42 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _