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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GGPS1 All Species: 25.15
Human Site: S292 Identified Species: 46.11
UniProt: O95749 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95749 NP_001032354.1 300 34871 S292 V A L V K H L S K M F K E E N
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536340 300 34834 S292 V A L I K H L S K M F K E E N
Cat Felis silvestris
Mouse Mus musculus Q9WTN0 300 34688 S292 V A L V K H L S K M F T E E N
Rat Rattus norvegicus Q6F596 300 34759 S292 V A L V K H L S K M F T E E N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512343 301 34844 S292 V A L I R H L S K M F R E D D
Chicken Gallus gallus XP_424685 420 47652 S412 V A L V E Q L S K M F K E N D
Frog Xenopus laevis NP_001091413 296 34032 E289 P Q L V S L I E Q L S E M Y Q
Zebra Danio Brachydanio rerio NP_956329 327 37394 S293 E A L V E H L S R M Y K E P E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523958 338 38808 N301 P Y M D R L L N K L L S W K T
Honey Bee Apis mellifera XP_001122899 310 35895 D298 P L L I Q V L D N L K S W K H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781061 427 48903 A410 L E M R Q R T A D V Y G G R G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12051 335 38633 N303 V N M I K N D N E N K Y L P D
Red Bread Mold Neurospora crassa P24322 433 48467 A426 L H Q E E N V A Q K N G K K E
Conservation
Percent
Protein Identity: 100 N.A. N.A. 98 N.A. 93.6 95 N.A. 92 64 83.6 77 N.A. 52.6 57.4 N.A. 48.2
Protein Similarity: 100 N.A. N.A. 99.6 N.A. 97.3 97.3 N.A. 96.3 69 93.3 85 N.A. 69.8 74.1 N.A. 59.4
P-Site Identity: 100 N.A. N.A. 93.3 N.A. 93.3 93.3 N.A. 66.6 73.3 13.3 60 N.A. 13.3 13.3 N.A. 0
P-Site Similarity: 100 N.A. N.A. 100 N.A. 93.3 93.3 N.A. 100 86.6 40 80 N.A. 46.6 46.6 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 39.7 36.9
Protein Similarity: N.A. N.A. N.A. N.A. 56.1 50.8
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 0
P-Site Similarity: N.A. N.A. N.A. N.A. 53.3 53.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 54 0 0 0 0 0 16 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 8 8 8 0 0 0 0 8 24 % D
% Glu: 8 8 0 8 24 0 0 8 8 0 0 8 54 31 16 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 47 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 16 8 0 8 % G
% His: 0 8 0 0 0 47 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 0 31 0 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 39 0 0 0 54 8 16 31 8 24 0 % K
% Leu: 16 8 70 0 0 16 70 0 0 24 8 0 8 0 0 % L
% Met: 0 0 24 0 0 0 0 0 0 54 0 0 8 0 0 % M
% Asn: 0 8 0 0 0 16 0 16 8 8 8 0 0 8 31 % N
% Pro: 24 0 0 0 0 0 0 0 0 0 0 0 0 16 0 % P
% Gln: 0 8 8 0 16 8 0 0 16 0 0 0 0 0 8 % Q
% Arg: 0 0 0 8 16 8 0 0 8 0 0 8 0 8 0 % R
% Ser: 0 0 0 0 8 0 0 54 0 0 8 16 0 0 0 % S
% Thr: 0 0 0 0 0 0 8 0 0 0 0 16 0 0 8 % T
% Val: 54 0 0 47 0 8 8 0 0 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 16 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 16 8 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _