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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGF19
All Species:
6.97
Human Site:
Y154
Identified Species:
19.17
UniProt:
O95750
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95750
NP_005108.1
216
24003
Y154
S
A
K
Q
R
Q
L
Y
K
N
R
G
F
L
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001100825
216
23988
Y154
S
A
K
Q
R
Q
L
Y
K
N
R
G
F
L
P
Dog
Lupus familis
XP_540802
256
27819
E190
T
K
I
G
L
V
M
E
Y
R
T
T
Q
G
R
Cat
Felis silvestris
Mouse
Mus musculus
O35622
218
25217
L161
Q
A
K
P
R
E
Q
L
Q
D
Q
K
P
S
N
Rat
Rattus norvegicus
Q8VI82
251
27893
P147
R
S
K
R
I
F
Q
P
G
T
N
P
P
P
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506714
272
30387
F207
S
A
K
Q
R
Q
Q
F
K
G
R
D
F
L
P
Chicken
Gallus gallus
P48801
220
25031
E152
T
K
R
K
A
S
A
E
R
L
W
Y
V
S
V
Frog
Xenopus laevis
P12226
155
17223
C101
L
R
C
I
T
D
E
C
F
F
F
E
R
L
E
Zebra Danio
Brachydanio rerio
P48802
256
28905
S174
G
S
K
R
R
A
S
S
K
R
Q
W
Y
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.1
62.8
N.A.
52.7
29.4
N.A.
45.2
25.4
25
23
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
98.1
67.5
N.A.
68.3
41
N.A.
56.2
40
40.7
37.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
0
N.A.
20
6.6
N.A.
73.3
0
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
13.3
N.A.
46.6
20
N.A.
80
26.6
6.6
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
45
0
0
12
12
12
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
12
0
0
0
0
12
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
12
0
0
0
12
0
12
0
0
0
% D
% Glu:
0
0
0
0
0
12
12
23
0
0
0
12
0
0
12
% E
% Phe:
0
0
0
0
0
12
0
12
12
12
12
0
34
0
12
% F
% Gly:
12
0
0
12
0
0
0
0
12
12
0
23
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
12
12
12
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
23
67
12
0
0
0
0
45
0
0
12
0
0
0
% K
% Leu:
12
0
0
0
12
0
23
12
0
12
0
0
0
45
0
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
23
12
0
0
0
12
% N
% Pro:
0
0
0
12
0
0
0
12
0
0
0
12
23
12
34
% P
% Gln:
12
0
0
34
0
34
34
0
12
0
23
0
12
0
0
% Q
% Arg:
12
12
12
23
56
0
0
0
12
23
34
0
12
0
12
% R
% Ser:
34
23
0
0
0
12
12
12
0
0
0
0
0
23
12
% S
% Thr:
23
0
0
0
12
0
0
0
0
12
12
12
0
0
0
% T
% Val:
0
0
0
0
0
12
0
0
0
0
0
0
12
12
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
12
12
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
23
12
0
0
12
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _