KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPA4L
All Species:
18.18
Human Site:
S409
Identified Species:
28.57
UniProt:
O95757
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95757
NP_055093.2
839
94486
S409
I
T
L
R
W
K
T
S
F
E
D
G
S
G
E
Chimpanzee
Pan troglodytes
XP_001157094
840
94684
S409
I
T
L
R
W
K
T
S
F
E
D
G
S
G
E
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
P409
I
S
L
R
W
N
S
P
A
E
E
G
S
S
D
Dog
Lupus familis
XP_533297
840
94621
S409
I
T
L
R
W
K
T
S
F
E
D
G
T
G
E
Cat
Felis silvestris
Mouse
Mus musculus
P48722
838
94364
S409
V
T
L
R
W
K
T
S
F
E
E
G
T
G
E
Rat
Rattus norvegicus
O88600
840
94038
P409
I
S
L
R
W
N
S
P
A
E
E
G
S
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510127
834
93982
P403
I
S
L
R
W
N
S
P
A
E
E
G
L
S
D
Chicken
Gallus gallus
NP_001012594
843
94794
S409
I
T
L
R
W
K
S
S
Y
E
E
G
T
G
E
Frog
Xenopus laevis
P02827
647
70897
N257
H
K
K
D
I
G
Q
N
K
R
A
L
R
R
L
Zebra Danio
Brachydanio rerio
XP_690505
826
93290
P409
I
T
L
R
W
K
S
P
T
D
E
S
V
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VG58
641
70235
L251
K
R
K
Y
K
K
D
L
R
S
N
P
R
A
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
A384
R
G
A
A
M
Q
C
A
I
L
S
P
T
F
R
Sea Urchin
Strong. purpuratus
Q06068
889
98600
K407
Y
P
I
E
L
E
W
K
G
T
E
G
E
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32590
693
77602
R303
D
V
S
S
Q
L
S
R
E
E
L
E
E
L
V
Red Bread Mold
Neurospora crassa
O74225
707
78655
V317
P
L
L
A
K
V
H
V
P
L
E
Q
A
L
A
Conservation
Percent
Protein Identity:
100
99.2
63.8
95.9
N.A.
92.6
63.3
N.A.
60.1
81.6
28.7
65.7
N.A.
28
N.A.
43
49.6
Protein Similarity:
100
99.4
79.2
98.3
N.A.
96.5
79
N.A.
75.9
91.4
47.2
81.6
N.A.
46.9
N.A.
58.8
67.9
P-Site Identity:
100
100
46.6
93.3
N.A.
80
46.6
N.A.
40
73.3
0
53.3
N.A.
6.6
N.A.
0
6.6
P-Site Similarity:
100
100
73.3
100
N.A.
100
73.3
N.A.
66.6
100
6.6
73.3
N.A.
13.3
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.8
38.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.2
55.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
14
0
0
0
7
20
0
7
0
7
7
7
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
7
0
0
7
0
0
7
20
0
0
7
20
% D
% Glu:
0
0
0
7
0
7
0
0
7
60
54
7
14
0
40
% E
% Phe:
0
0
0
0
0
0
0
0
27
0
0
0
0
7
0
% F
% Gly:
0
7
0
0
0
7
0
0
7
0
0
60
0
40
7
% G
% His:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
54
0
7
0
7
0
0
0
7
0
0
0
0
0
0
% I
% Lys:
7
7
14
0
14
47
0
7
7
0
0
0
0
0
0
% K
% Leu:
0
7
67
0
7
7
0
7
0
14
7
7
7
14
14
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
20
0
7
0
0
7
0
0
0
0
% N
% Pro:
7
7
0
0
0
0
0
27
7
0
0
14
0
0
0
% P
% Gln:
0
0
0
0
7
7
7
0
0
0
0
7
0
0
0
% Q
% Arg:
7
7
0
60
0
0
0
7
7
7
0
0
14
7
7
% R
% Ser:
0
20
7
7
0
0
40
34
0
7
7
7
27
20
0
% S
% Thr:
0
40
0
0
0
0
27
0
7
7
0
0
27
0
0
% T
% Val:
7
7
0
0
0
7
0
7
0
0
0
0
7
0
7
% V
% Trp:
0
0
0
0
60
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
7
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _