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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPA4L
All Species:
9.7
Human Site:
S508
Identified Species:
15.24
UniProt:
O95757
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95757
NP_055093.2
839
94486
S508
Q
N
L
E
G
D
H
S
D
A
P
M
E
T
E
Chimpanzee
Pan troglodytes
XP_001157094
840
94684
S508
Q
N
L
E
G
D
H
S
D
A
S
M
E
T
E
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
E508
H
K
S
E
E
N
E
E
P
M
E
T
D
Q
N
Dog
Lupus familis
XP_533297
840
94621
S508
Q
N
V
E
G
D
H
S
D
A
P
M
E
T
E
Cat
Felis silvestris
Mouse
Mus musculus
P48722
838
94364
N508
Q
N
L
E
G
D
H
N
D
A
A
M
E
T
E
Rat
Rattus norvegicus
O88600
840
94038
E508
H
K
S
E
E
S
E
E
P
M
E
T
D
Q
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510127
834
93982
E502
H
K
S
D
E
S
E
E
P
M
E
T
D
Q
H
Chicken
Gallus gallus
NP_001012594
843
94794
N508
Q
N
I
D
G
D
H
N
D
A
A
M
D
T
E
Frog
Xenopus laevis
P02827
647
70897
N356
K
L
L
Q
D
F
F
N
G
R
E
L
N
K
S
Zebra Danio
Brachydanio rerio
XP_690505
826
93290
V508
Q
K
G
E
P
E
D
V
Q
M
D
T
E
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VG58
641
70235
E350
K
V
Q
S
L
L
Q
E
F
F
H
G
K
N
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
K483
G
N
Q
K
V
K
V
K
V
R
V
N
P
D
G
Sea Urchin
Strong. purpuratus
Q06068
889
98600
A506
L
P
V
Q
A
E
D
A
M
E
D
G
S
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32590
693
77602
V402
E
D
I
D
P
Y
S
V
S
Y
T
W
D
K
Q
Red Bread Mold
Neurospora crassa
O74225
707
78655
S416
D
I
P
D
E
D
T
S
L
V
V
F
N
K
G
Conservation
Percent
Protein Identity:
100
99.2
63.8
95.9
N.A.
92.6
63.3
N.A.
60.1
81.6
28.7
65.7
N.A.
28
N.A.
43
49.6
Protein Similarity:
100
99.4
79.2
98.3
N.A.
96.5
79
N.A.
75.9
91.4
47.2
81.6
N.A.
46.9
N.A.
58.8
67.9
P-Site Identity:
100
93.3
6.6
93.3
N.A.
86.6
6.6
N.A.
0
66.6
6.6
20
N.A.
0
N.A.
6.6
6.6
P-Site Similarity:
100
93.3
20
100
N.A.
93.3
13.3
N.A.
13.3
93.3
33.3
26.6
N.A.
13.3
N.A.
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.8
38.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.2
55.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
7
0
34
14
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
27
7
40
14
0
34
0
14
0
34
7
0
% D
% Glu:
7
0
0
47
27
14
20
27
0
7
27
0
34
0
40
% E
% Phe:
0
0
0
0
0
7
7
0
7
7
0
7
0
0
0
% F
% Gly:
7
0
7
0
34
0
0
0
7
0
0
14
0
0
14
% G
% His:
20
0
0
0
0
0
34
0
0
0
7
0
0
0
7
% H
% Ile:
0
7
14
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
14
27
0
7
0
7
0
7
0
0
0
0
7
20
0
% K
% Leu:
7
7
27
0
7
7
0
0
7
0
0
7
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
7
27
0
34
0
0
0
% M
% Asn:
0
40
0
0
0
7
0
20
0
0
0
7
14
7
14
% N
% Pro:
0
7
7
0
14
0
0
0
20
0
14
0
7
14
0
% P
% Gln:
40
0
14
14
0
0
7
0
7
0
0
0
0
20
7
% Q
% Arg:
0
0
0
0
0
0
0
0
0
14
0
0
0
0
0
% R
% Ser:
0
0
20
7
0
14
7
27
7
0
7
0
7
0
7
% S
% Thr:
0
0
0
0
0
0
7
0
0
0
7
27
0
34
7
% T
% Val:
0
7
14
0
7
0
7
14
7
7
14
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _