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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPA4L
All Species:
12.12
Human Site:
S517
Identified Species:
19.05
UniProt:
O95757
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95757
NP_055093.2
839
94486
S517
A
P
M
E
T
E
T
S
F
K
N
E
N
K
D
Chimpanzee
Pan troglodytes
XP_001157094
840
94684
S517
A
S
M
E
T
E
T
S
F
K
N
E
N
K
D
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
K517
M
E
T
D
Q
N
A
K
E
E
E
K
M
Q
V
Dog
Lupus familis
XP_533297
840
94621
S517
A
P
M
E
T
E
T
S
F
K
N
E
G
K
D
Cat
Felis silvestris
Mouse
Mus musculus
P48722
838
94364
P517
A
A
M
E
T
E
A
P
K
S
E
G
K
E
D
Rat
Rattus norvegicus
O88600
840
94038
K517
M
E
T
D
Q
N
A
K
E
E
E
K
M
Q
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510127
834
93982
K511
M
E
T
D
Q
H
A
K
E
E
E
K
M
Q
V
Chicken
Gallus gallus
NP_001012594
843
94794
S517
A
A
M
D
T
E
S
S
S
K
N
Q
G
R
E
Frog
Xenopus laevis
P02827
647
70897
N365
R
E
L
N
K
S
I
N
P
D
E
A
V
A
Y
Zebra Danio
Brachydanio rerio
XP_690505
826
93290
Q517
M
D
T
E
P
T
V
Q
N
E
G
R
P
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VG58
641
70235
L359
F
H
G
K
N
L
N
L
S
I
N
P
D
E
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
F492
R
V
N
P
D
G
I
F
T
I
A
S
A
T
M
Sea Urchin
Strong. purpuratus
Q06068
889
98600
N515
E
D
G
S
P
E
E
N
G
P
S
K
E
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32590
693
77602
D411
Y
T
W
D
K
Q
V
D
D
E
D
R
L
E
V
Red Bread Mold
Neurospora crassa
O74225
707
78655
V425
V
V
F
N
K
G
N
V
L
P
S
T
K
I
L
Conservation
Percent
Protein Identity:
100
99.2
63.8
95.9
N.A.
92.6
63.3
N.A.
60.1
81.6
28.7
65.7
N.A.
28
N.A.
43
49.6
Protein Similarity:
100
99.4
79.2
98.3
N.A.
96.5
79
N.A.
75.9
91.4
47.2
81.6
N.A.
46.9
N.A.
58.8
67.9
P-Site Identity:
100
93.3
0
93.3
N.A.
40
0
N.A.
0
46.6
0
6.6
N.A.
6.6
N.A.
0
6.6
P-Site Similarity:
100
93.3
26.6
93.3
N.A.
46.6
26.6
N.A.
26.6
80
13.3
26.6
N.A.
26.6
N.A.
0
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.8
38.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.2
55.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
14
0
0
0
0
27
0
0
0
7
7
7
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
14
0
34
7
0
0
7
7
7
7
0
7
0
27
% D
% Glu:
7
27
0
34
0
40
7
0
20
34
34
20
7
34
14
% E
% Phe:
7
0
7
0
0
0
0
7
20
0
0
0
0
0
0
% F
% Gly:
0
0
14
0
0
14
0
0
7
0
7
7
14
0
7
% G
% His:
0
7
0
0
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
14
0
0
14
0
0
0
7
0
% I
% Lys:
0
0
0
7
20
0
0
20
7
27
0
27
14
20
0
% K
% Leu:
0
0
7
0
0
7
0
7
7
0
0
0
7
0
7
% L
% Met:
27
0
34
0
0
0
0
0
0
0
0
0
20
0
7
% M
% Asn:
0
0
7
14
7
14
14
14
7
0
34
0
14
0
0
% N
% Pro:
0
14
0
7
14
0
0
7
7
14
0
7
7
0
0
% P
% Gln:
0
0
0
0
20
7
0
7
0
0
0
7
0
20
0
% Q
% Arg:
14
0
0
0
0
0
0
0
0
0
0
14
0
7
0
% R
% Ser:
0
7
0
7
0
7
7
27
14
7
14
7
0
0
0
% S
% Thr:
0
7
27
0
34
7
20
0
7
0
0
7
0
7
0
% T
% Val:
7
14
0
0
0
0
14
7
0
0
0
0
7
0
27
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _