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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPA4L
All Species:
20.3
Human Site:
S587
Identified Species:
31.9
UniProt:
O95757
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95757
NP_055093.2
839
94486
S587
I
D
L
P
I
Q
S
S
L
C
R
Q
L
G
Q
Chimpanzee
Pan troglodytes
XP_001157094
840
94684
S588
I
D
L
P
I
Q
S
S
L
C
R
Q
L
G
Q
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
Q584
V
D
L
P
I
E
N
Q
L
L
W
Q
I
D
R
Dog
Lupus familis
XP_533297
840
94621
S588
I
D
L
P
I
Q
S
S
L
C
R
Q
L
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
P48722
838
94364
S587
I
D
L
P
I
Q
S
S
L
Y
R
Q
L
T
Q
Rat
Rattus norvegicus
O88600
840
94038
Q584
V
D
L
P
I
E
S
Q
L
L
W
Q
L
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510127
834
93982
Q578
V
D
L
P
I
E
N
Q
L
L
W
Q
I
G
R
Chicken
Gallus gallus
NP_001012594
843
94794
S590
I
D
L
P
I
Q
A
S
L
Y
R
Q
L
G
Q
Frog
Xenopus laevis
P02827
647
70897
P422
I
K
R
N
T
T
I
P
T
K
Q
T
Q
S
F
Zebra Danio
Brachydanio rerio
XP_690505
826
93290
N579
V
D
L
P
I
L
A
N
T
T
R
Q
L
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VG58
641
70235
C416
T
K
L
I
E
R
N
C
R
I
P
C
K
Q
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
S550
V
I
E
S
I
P
V
S
Y
D
V
Q
K
F
H
Sea Urchin
Strong. purpuratus
Q06068
889
98600
S575
K
D
Q
T
S
E
S
S
K
S
D
K
E
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32590
693
77602
K468
K
W
S
F
T
G
V
K
V
P
K
D
Q
D
F
Red Bread Mold
Neurospora crassa
O74225
707
78655
L482
E
D
F
M
I
C
K
L
K
A
R
I
N
I
H
Conservation
Percent
Protein Identity:
100
99.2
63.8
95.9
N.A.
92.6
63.3
N.A.
60.1
81.6
28.7
65.7
N.A.
28
N.A.
43
49.6
Protein Similarity:
100
99.4
79.2
98.3
N.A.
96.5
79
N.A.
75.9
91.4
47.2
81.6
N.A.
46.9
N.A.
58.8
67.9
P-Site Identity:
100
100
40
100
N.A.
86.6
53.3
N.A.
46.6
86.6
6.6
46.6
N.A.
6.6
N.A.
20
20
P-Site Similarity:
100
100
73.3
100
N.A.
86.6
73.3
N.A.
80
93.3
13.3
73.3
N.A.
20
N.A.
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.8
38.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.2
55.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
14
0
0
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
7
0
7
0
20
0
7
0
0
0
% C
% Asp:
0
74
0
0
0
0
0
0
0
7
7
7
0
27
0
% D
% Glu:
7
0
7
0
7
27
0
0
0
0
0
0
7
0
0
% E
% Phe:
0
0
7
7
0
0
0
0
0
0
0
0
0
7
14
% F
% Gly:
0
0
0
0
0
7
0
0
0
0
0
0
0
34
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
14
% H
% Ile:
40
7
0
7
74
0
7
0
0
7
0
7
14
7
0
% I
% Lys:
14
14
0
0
0
0
7
7
14
7
7
7
14
0
7
% K
% Leu:
0
0
67
0
0
7
0
7
54
20
0
0
47
0
0
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
20
7
0
0
0
0
7
0
0
% N
% Pro:
0
0
0
60
0
7
0
7
0
7
7
0
0
0
0
% P
% Gln:
0
0
7
0
0
34
0
20
0
0
7
67
14
7
34
% Q
% Arg:
0
0
7
0
0
7
0
0
7
0
47
0
0
0
27
% R
% Ser:
0
0
7
7
7
0
40
47
0
7
0
0
0
14
0
% S
% Thr:
7
0
0
7
14
7
0
0
14
7
0
7
0
7
7
% T
% Val:
34
0
0
0
0
0
14
0
7
0
7
0
0
0
0
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
20
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
14
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _