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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPA4L
All Species:
19.7
Human Site:
S775
Identified Species:
30.95
UniProt:
O95757
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95757
NP_055093.2
839
94486
S775
V
S
E
I
V
A
K
S
K
E
L
D
N
F
C
Chimpanzee
Pan troglodytes
XP_001157094
840
94684
S776
V
S
E
I
V
A
K
S
K
E
L
D
N
F
C
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
I772
S
K
E
I
E
A
K
I
K
E
L
T
S
I
C
Dog
Lupus familis
XP_533297
840
94621
S776
V
S
E
I
V
A
K
S
K
D
L
D
N
F
C
Cat
Felis silvestris
Mouse
Mus musculus
P48722
838
94364
S775
V
S
E
I
V
T
K
S
K
E
L
D
N
F
C
Rat
Rattus norvegicus
O88600
840
94038
I772
T
K
E
I
E
A
K
I
K
E
L
T
N
I
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510127
834
93982
I766
T
K
D
V
E
A
K
I
K
E
L
A
S
L
C
Chicken
Gallus gallus
NP_001012594
843
94794
S778
V
A
E
I
I
S
K
S
K
E
L
D
S
F
C
Frog
Xenopus laevis
P02827
647
70897
Q586
I
S
W
L
E
N
N
Q
L
A
E
K
E
E
Y
Zebra Danio
Brachydanio rerio
XP_690505
826
93290
V760
A
Q
D
P
A
V
K
V
A
D
I
I
Q
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VG58
641
70235
S580
E
T
I
R
W
L
D
S
N
T
T
A
E
K
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
R714
A
R
H
K
Q
E
T
R
S
K
T
D
A
P
V
Sea Urchin
Strong. purpuratus
Q06068
889
98600
I807
A
A
Q
I
R
S
E
I
Q
S
M
K
F
V
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32590
693
77602
A632
I
A
K
Y
E
E
L
A
S
L
G
N
I
I
R
Red Bread Mold
Neurospora crassa
O74225
707
78655
Y646
A
G
P
V
V
Q
R
Y
F
D
K
V
E
A
E
Conservation
Percent
Protein Identity:
100
99.2
63.8
95.9
N.A.
92.6
63.3
N.A.
60.1
81.6
28.7
65.7
N.A.
28
N.A.
43
49.6
Protein Similarity:
100
99.4
79.2
98.3
N.A.
96.5
79
N.A.
75.9
91.4
47.2
81.6
N.A.
46.9
N.A.
58.8
67.9
P-Site Identity:
100
100
53.3
93.3
N.A.
93.3
60
N.A.
40
73.3
6.6
6.6
N.A.
6.6
N.A.
6.6
13.3
P-Site Similarity:
100
100
60
100
N.A.
93.3
60
N.A.
60
100
20
26.6
N.A.
13.3
N.A.
13.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.8
38.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.2
55.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
27
20
0
0
7
40
0
7
7
7
0
14
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% C
% Asp:
0
0
14
0
0
0
7
0
0
20
0
40
0
0
0
% D
% Glu:
7
0
47
0
34
14
7
0
0
47
7
0
20
7
14
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
0
0
7
34
0
% F
% Gly:
0
7
0
0
0
0
0
0
0
0
7
0
0
0
0
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
14
0
7
54
7
0
0
27
0
0
7
7
7
20
7
% I
% Lys:
0
20
7
7
0
0
60
0
54
7
7
14
0
14
0
% K
% Leu:
0
0
0
7
0
7
7
0
7
7
54
0
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
7
0
7
0
0
7
34
0
0
% N
% Pro:
0
0
7
7
0
0
0
0
0
0
0
0
0
7
0
% P
% Gln:
0
7
7
0
7
7
0
7
7
0
0
0
7
0
0
% Q
% Arg:
0
7
0
7
7
0
7
7
0
0
0
0
0
0
7
% R
% Ser:
7
34
0
0
0
14
0
40
14
7
0
0
20
0
0
% S
% Thr:
14
7
0
0
0
7
7
0
0
7
14
14
0
0
0
% T
% Val:
34
0
0
14
34
7
0
7
0
0
0
7
0
7
7
% V
% Trp:
0
0
7
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _