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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPA4L All Species: 15.45
Human Site: S827 Identified Species: 24.29
UniProt: O95757 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95757 NP_055093.2 839 94486 S827 S D S T K D S S Q H T K S S G
Chimpanzee Pan troglodytes XP_001157094 840 94684 S828 S D S T K D S S Q H T K S S G
Rhesus Macaque Macaca mulatta XP_001106968 840 94362 D823 Q A A E Q G T D T A V P S E S
Dog Lupus familis XP_533297 840 94621 S828 A D T T K D S S Q H T K S S G
Cat Felis silvestris
Mouse Mus musculus P48722 838 94364 S827 P D P P K G S S Q H T D S G E
Rat Rattus norvegicus O88600 840 94038 D823 Q A A E H G A D T A V P S D G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510127 834 93982 A816 A Q A A E Q K A N S T A P A D
Chicken Gallus gallus NP_001012594 843 94794 S831 P D P A K D N S Q Q T K P P G
Frog Xenopus laevis P02827 647 70897 G636 C G A Q A R Q G G N S G P T I
Zebra Danio Brachydanio rerio XP_690505 826 93290 Q814 G A D S K G N Q Q T K P P S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VG58 641 70235 G630 G Q Q A G G F G G Y S G P T V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q05036 776 86878 D764 E P Q P A A G D Q P Q S Q P G
Sea Urchin Strong. purpuratus Q06068 889 98600 A864 K M D T S D Q A P T G E A S K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32590 693 77602 S682 A R A A S D D S D D N N D E N
Red Bread Mold Neurospora crassa O74225 707 78655 D696 A K D D E M T D A D A P K P V
Conservation
Percent
Protein Identity: 100 99.2 63.8 95.9 N.A. 92.6 63.3 N.A. 60.1 81.6 28.7 65.7 N.A. 28 N.A. 43 49.6
Protein Similarity: 100 99.4 79.2 98.3 N.A. 96.5 79 N.A. 75.9 91.4 47.2 81.6 N.A. 46.9 N.A. 58.8 67.9
P-Site Identity: 100 100 6.6 86.6 N.A. 53.3 13.3 N.A. 6.6 53.3 0 26.6 N.A. 0 N.A. 13.3 20
P-Site Similarity: 100 100 26.6 100 N.A. 53.3 26.6 N.A. 40 60 26.6 40 N.A. 20 N.A. 13.3 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.8 38.3
Protein Similarity: N.A. N.A. N.A. N.A. 51.2 55.5
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 0
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 27 20 34 27 14 7 7 14 7 14 7 7 7 7 0 % A
% Cys: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 34 20 7 0 40 7 27 7 14 0 7 7 7 7 % D
% Glu: 7 0 0 14 14 0 0 0 0 0 0 7 0 14 7 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % F
% Gly: 14 7 0 0 7 34 7 14 14 0 7 14 0 7 47 % G
% His: 0 0 0 0 7 0 0 0 0 27 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % I
% Lys: 7 7 0 0 40 0 7 0 0 0 7 27 7 0 7 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 7 0 0 0 7 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 14 0 7 7 7 7 0 0 7 % N
% Pro: 14 7 14 14 0 0 0 0 7 7 0 27 34 20 0 % P
% Gln: 14 14 14 7 7 7 14 7 47 7 7 0 7 0 0 % Q
% Arg: 0 7 0 0 0 7 0 0 0 0 0 0 0 0 0 % R
% Ser: 14 0 14 7 14 0 27 40 0 7 14 7 40 34 7 % S
% Thr: 0 0 7 27 0 0 14 0 14 14 40 0 0 14 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 14 0 0 0 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _