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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPA4L All Species: 37.88
Human Site: T35 Identified Species: 59.52
UniProt: O95757 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95757 NP_055093.2 839 94486 T35 N E Y S D R C T P A C I S L G
Chimpanzee Pan troglodytes XP_001157094 840 94684 T35 N E Y S D R C T P A C I S L G
Rhesus Macaque Macaca mulatta XP_001106968 840 94362 T35 N E Y S D R C T P A C I S F G
Dog Lupus familis XP_533297 840 94621 T35 N E Y S D R C T P A C I S L G
Cat Felis silvestris
Mouse Mus musculus P48722 838 94364 T35 N E Y S D R C T P A C I S L G
Rat Rattus norvegicus O88600 840 94038 T35 N E Y S D R C T P A C V S F G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510127 834 93982 P37 T A C V S F G P K N R S I G A
Chicken Gallus gallus NP_001012594 843 94794 T35 N E Y S D R C T P A C I S L G
Frog Xenopus laevis P02827 647 70897
Zebra Danio Brachydanio rerio XP_690505 826 93290 T35 N E Y S D R C T P A C I S L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VG58 641 70235
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q05036 776 86878 T35 N D Y S L H A T P A C V S F G
Sea Urchin Strong. purpuratus Q06068 889 98600 T35 N E Y S D R L T P S V V S F G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32590 693 77602
Red Bread Mold Neurospora crassa O74225 707 78655
Conservation
Percent
Protein Identity: 100 99.2 63.8 95.9 N.A. 92.6 63.3 N.A. 60.1 81.6 28.7 65.7 N.A. 28 N.A. 43 49.6
Protein Similarity: 100 99.4 79.2 98.3 N.A. 96.5 79 N.A. 75.9 91.4 47.2 81.6 N.A. 46.9 N.A. 58.8 67.9
P-Site Identity: 100 100 93.3 100 N.A. 100 86.6 N.A. 0 100 0 93.3 N.A. 0 N.A. 60 66.6
P-Site Similarity: 100 100 93.3 100 N.A. 100 93.3 N.A. 0 100 0 93.3 N.A. 0 N.A. 73.3 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.8 38.3
Protein Similarity: N.A. N.A. N.A. N.A. 51.2 55.5
P-Site Identity: N.A. N.A. N.A. N.A. 0 0
P-Site Similarity: N.A. N.A. N.A. N.A. 0 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 0 7 0 0 60 0 0 0 0 14 % A
% Cys: 0 0 7 0 0 0 54 0 0 0 60 0 0 0 0 % C
% Asp: 0 7 0 0 60 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 60 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 7 0 0 0 0 0 0 0 27 0 % F
% Gly: 0 0 0 0 0 0 7 0 0 0 0 0 0 7 60 % G
% His: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 47 7 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 7 0 7 0 0 0 0 0 0 40 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 67 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 7 67 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 60 0 0 0 0 7 0 0 0 0 % R
% Ser: 0 0 0 67 7 0 0 0 0 7 0 7 67 0 0 % S
% Thr: 7 0 0 0 0 0 0 67 0 0 0 0 0 0 0 % T
% Val: 0 0 0 7 0 0 0 0 0 0 7 20 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 67 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _