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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPA4L All Species: 31.52
Human Site: T403 Identified Species: 49.52
UniProt: O95757 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95757 NP_055093.2 839 94486 T403 D L V P Y S I T L R W K T S F
Chimpanzee Pan troglodytes XP_001157094 840 94684 T403 D L V P Y S I T L R W K T S F
Rhesus Macaque Macaca mulatta XP_001106968 840 94362 S403 D V V P Y P I S L R W N S P A
Dog Lupus familis XP_533297 840 94621 T403 D L V P Y S I T L R W K T S F
Cat Felis silvestris
Mouse Mus musculus P48722 838 94364 T403 D L V P Y S V T L R W K T S F
Rat Rattus norvegicus O88600 840 94038 S403 D V V P Y P I S L R W N S P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510127 834 93982 S397 D V V P Y P I S L R W N S P A
Chicken Gallus gallus NP_001012594 843 94794 T403 D V V P Y S I T L R W K S S Y
Frog Xenopus laevis P02827 647 70897 K251 E E F K R K H K K D I G Q N K
Zebra Danio Brachydanio rerio XP_690505 826 93290 T403 D T V P F P I T L R W K S P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VG58 641 70235 R245 H L A E E F K R K Y K K D L R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q05036 776 86878 G378 Q D E A V A R G A A M Q C A I
Sea Urchin Strong. purpuratus Q06068 889 98600 P401 V T D L T P Y P I E L E W K G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32590 693 77602 V297 S V M D D I D V S S Q L S R E
Red Bread Mold Neurospora crassa O74225 707 78655 L311 F E A M V E P L L A K V H V P
Conservation
Percent
Protein Identity: 100 99.2 63.8 95.9 N.A. 92.6 63.3 N.A. 60.1 81.6 28.7 65.7 N.A. 28 N.A. 43 49.6
Protein Similarity: 100 99.4 79.2 98.3 N.A. 96.5 79 N.A. 75.9 91.4 47.2 81.6 N.A. 46.9 N.A. 58.8 67.9
P-Site Identity: 100 100 53.3 100 N.A. 93.3 53.3 N.A. 53.3 80 0 60 N.A. 13.3 N.A. 0 0
P-Site Similarity: 100 100 73.3 100 N.A. 100 73.3 N.A. 73.3 100 13.3 73.3 N.A. 13.3 N.A. 20 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.8 38.3
Protein Similarity: N.A. N.A. N.A. N.A. 51.2 55.5
P-Site Identity: N.A. N.A. N.A. N.A. 0 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 20 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 14 7 0 7 0 0 7 14 0 0 0 7 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % C
% Asp: 60 7 7 7 7 0 7 0 0 7 0 0 7 0 0 % D
% Glu: 7 14 7 7 7 7 0 0 0 7 0 7 0 0 7 % E
% Phe: 7 0 7 0 7 7 0 0 0 0 0 0 0 0 27 % F
% Gly: 0 0 0 0 0 0 0 7 0 0 0 7 0 0 7 % G
% His: 7 0 0 0 0 0 7 0 0 0 0 0 7 0 0 % H
% Ile: 0 0 0 0 0 7 54 0 7 0 7 0 0 0 7 % I
% Lys: 0 0 0 7 0 7 7 7 14 0 14 47 0 7 7 % K
% Leu: 0 34 0 7 0 0 0 7 67 0 7 7 0 7 0 % L
% Met: 0 0 7 7 0 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 20 0 7 0 % N
% Pro: 0 0 0 60 0 34 7 7 0 0 0 0 0 27 7 % P
% Gln: 7 0 0 0 0 0 0 0 0 0 7 7 7 0 0 % Q
% Arg: 0 0 0 0 7 0 7 7 0 60 0 0 0 7 7 % R
% Ser: 7 0 0 0 0 34 0 20 7 7 0 0 40 34 0 % S
% Thr: 0 14 0 0 7 0 0 40 0 0 0 0 27 0 7 % T
% Val: 7 34 60 0 14 0 7 7 0 0 0 7 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 60 0 7 0 0 % W
% Tyr: 0 0 0 0 54 0 7 0 0 7 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _