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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPA4L All Species: 39.09
Human Site: T433 Identified Species: 61.43
UniProt: O95757 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95757 NP_055093.2 839 94486 T433 A P F S K V I T F H K K E P F
Chimpanzee Pan troglodytes XP_001157094 840 94684 T433 A P F S K V I T F H K K E P F
Rhesus Macaque Macaca mulatta XP_001106968 840 94362 T433 A P F S K V L T F Y R K E P F
Dog Lupus familis XP_533297 840 94621 T433 A P F S K V I T F H K K E P F
Cat Felis silvestris
Mouse Mus musculus P48722 838 94364 T433 A P F S K V I T F H K K E P F
Rat Rattus norvegicus O88600 840 94038 T433 A P F S K V L T F Y R K E P F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510127 834 93982 T427 A P F S K V L T F Y R K E P F
Chicken Gallus gallus NP_001012594 843 94794 T433 A P F S K V I T F H K K E P F
Frog Xenopus laevis P02827 647 70897 A281 T L S S S S Q A S I E I D S L
Zebra Danio Brachydanio rerio XP_690505 826 93290 T433 A P F S K I I T F H K K E P F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VG58 641 70235 S275 A K R T L S S S T E A T I E I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q05036 776 86878 S408 Q P Y R I R L S W N S T G E N
Sea Urchin Strong. purpuratus Q06068 889 98600 L431 Q A P F S K M L T F Y R K A P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32590 693 77602 Q327 P I T N A L A Q A K L T V N D
Red Bread Mold Neurospora crassa O74225 707 78655 G341 D I I E V V G G G S R V P S V
Conservation
Percent
Protein Identity: 100 99.2 63.8 95.9 N.A. 92.6 63.3 N.A. 60.1 81.6 28.7 65.7 N.A. 28 N.A. 43 49.6
Protein Similarity: 100 99.4 79.2 98.3 N.A. 96.5 79 N.A. 75.9 91.4 47.2 81.6 N.A. 46.9 N.A. 58.8 67.9
P-Site Identity: 100 100 80 100 N.A. 100 80 N.A. 80 100 6.6 93.3 N.A. 6.6 N.A. 6.6 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 20 100 N.A. 20 N.A. 40 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.8 38.3
Protein Similarity: N.A. N.A. N.A. N.A. 51.2 55.5
P-Site Identity: N.A. N.A. N.A. N.A. 0 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 67 7 0 0 7 0 7 7 7 0 7 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 0 0 0 0 0 0 0 7 0 7 % D
% Glu: 0 0 0 7 0 0 0 0 0 7 7 0 60 14 0 % E
% Phe: 0 0 60 7 0 0 0 0 60 7 0 0 0 0 60 % F
% Gly: 0 0 0 0 0 0 7 7 7 0 0 0 7 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 40 0 0 0 0 0 % H
% Ile: 0 14 7 0 7 7 40 0 0 7 0 7 7 0 7 % I
% Lys: 0 7 0 0 60 7 0 0 0 7 40 60 7 0 0 % K
% Leu: 0 7 0 0 7 7 27 7 0 0 7 0 0 0 7 % L
% Met: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 0 0 0 0 0 7 0 0 0 7 7 % N
% Pro: 7 67 7 0 0 0 0 0 0 0 0 0 7 60 7 % P
% Gln: 14 0 0 0 0 0 7 7 0 0 0 0 0 0 0 % Q
% Arg: 0 0 7 7 0 7 0 0 0 0 27 7 0 0 0 % R
% Ser: 0 0 7 67 14 14 7 14 7 7 7 0 0 14 0 % S
% Thr: 7 0 7 7 0 0 0 60 14 0 0 20 0 0 0 % T
% Val: 0 0 0 0 7 60 0 0 0 0 0 7 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 0 0 20 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _