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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPA4L All Species: 17.58
Human Site: T571 Identified Species: 27.62
UniProt: O95757 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95757 NP_055093.2 839 94486 T571 K Q D R L N Q T L K K G K V K
Chimpanzee Pan troglodytes XP_001157094 840 94684 T572 K Q D R L N Q T L K K G K V K
Rhesus Macaque Macaca mulatta XP_001106968 840 94362 K568 M D Q P P Q A K K A K V K T S
Dog Lupus familis XP_533297 840 94621 T572 K Q D R L N Q T I K K G K V K
Cat Felis silvestris
Mouse Mus musculus P48722 838 94364 T571 K Q D R I N Q T I K K G K I K
Rat Rattus norvegicus O88600 840 94038 K568 M D Q P P Q A K K A K V K T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510127 834 93982 K562 M D Q P P Q A K K A K V K T S
Chicken Gallus gallus NP_001012594 843 94794 P574 K Q D H P T L P R A K T K V K
Frog Xenopus laevis P02827 647 70897 T406 P L S L G L E T A G G V M T V
Zebra Danio Brachydanio rerio XP_690505 826 93290 S563 Q D Q G A S S S K A K S K V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VG58 641 70235 G400 D V A P L S L G I E T A G G V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q05036 776 86878 T534 P L E P V K K T K L V P V D L
Sea Urchin Strong. purpuratus Q06068 889 98600 G559 K E E Q A D N G S K E T S K D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32590 693 77602 P452 Y T H P S K L P K G T S T T I
Red Bread Mold Neurospora crassa O74225 707 78655 K466 F I G R F S I K G V H A T E G
Conservation
Percent
Protein Identity: 100 99.2 63.8 95.9 N.A. 92.6 63.3 N.A. 60.1 81.6 28.7 65.7 N.A. 28 N.A. 43 49.6
Protein Similarity: 100 99.4 79.2 98.3 N.A. 96.5 79 N.A. 75.9 91.4 47.2 81.6 N.A. 46.9 N.A. 58.8 67.9
P-Site Identity: 100 100 13.3 93.3 N.A. 80 13.3 N.A. 13.3 46.6 6.6 26.6 N.A. 6.6 N.A. 6.6 13.3
P-Site Similarity: 100 100 13.3 100 N.A. 100 13.3 N.A. 13.3 46.6 13.3 46.6 N.A. 26.6 N.A. 26.6 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.8 38.3
Protein Similarity: N.A. N.A. N.A. N.A. 51.2 55.5
P-Site Identity: N.A. N.A. N.A. N.A. 0 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 0 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 14 0 20 0 7 34 0 14 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 27 34 0 0 7 0 0 0 0 0 0 0 7 7 % D
% Glu: 0 7 14 0 0 0 7 0 0 7 7 0 0 7 0 % E
% Phe: 7 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 7 7 7 0 0 14 7 14 7 27 7 7 7 % G
% His: 0 0 7 7 0 0 0 0 0 0 7 0 0 0 0 % H
% Ile: 0 7 0 0 7 0 7 0 20 0 0 0 0 7 7 % I
% Lys: 40 0 0 0 0 14 7 27 40 34 60 0 60 7 40 % K
% Leu: 0 14 0 7 27 7 20 0 14 7 0 0 0 0 7 % L
% Met: 20 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 0 0 0 0 0 27 7 0 0 0 0 0 0 0 0 % N
% Pro: 14 0 0 40 27 0 0 14 0 0 0 7 0 0 0 % P
% Gln: 7 34 27 7 0 20 27 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 34 0 0 0 0 7 0 0 0 0 0 0 % R
% Ser: 0 0 7 0 7 20 7 7 7 0 0 14 7 0 20 % S
% Thr: 0 7 0 0 0 7 0 40 0 0 14 14 14 34 0 % T
% Val: 0 7 0 0 7 0 0 0 0 7 7 27 7 34 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _