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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPA4L
All Species:
32.42
Human Site:
T644
Identified Species:
50.95
UniProt:
O95757
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95757
NP_055093.2
839
94486
T644
T
V
Y
E
K
F
I
T
P
E
D
L
S
K
L
Chimpanzee
Pan troglodytes
XP_001157094
840
94684
T645
T
V
Y
E
K
F
I
T
P
E
D
L
S
K
L
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
S641
G
E
Y
E
K
F
V
S
E
D
D
R
N
S
F
Dog
Lupus familis
XP_533297
840
94621
T645
T
V
Y
E
K
F
I
T
Q
E
D
L
N
K
L
Cat
Felis silvestris
Mouse
Mus musculus
P48722
838
94364
T644
T
V
Y
E
K
F
I
T
P
E
D
M
N
K
L
Rat
Rattus norvegicus
O88600
840
94038
S641
G
E
Y
E
K
F
V
S
E
D
D
R
N
N
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510127
834
93982
S635
G
V
Y
E
K
F
V
S
E
D
D
R
N
S
F
Chicken
Gallus gallus
NP_001012594
843
94794
T647
G
V
F
E
K
F
I
T
E
E
D
T
N
K
L
Frog
Xenopus laevis
P02827
647
70897
P467
F
E
L
S
G
I
P
P
A
P
R
G
V
P
Q
Zebra Danio
Brachydanio rerio
XP_690505
826
93290
T636
G
I
Y
E
K
Y
V
T
E
D
E
S
N
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VG58
641
70235
G461
L
G
T
F
D
L
S
G
I
P
P
A
P
R
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
Y595
R
D
K
V
S
D
Q
Y
A
E
F
I
T
P
A
Sea Urchin
Strong. purpuratus
Q06068
889
98600
S676
D
K
F
E
Q
Y
I
S
E
K
E
R
G
S
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32590
693
77602
A513
P
V
P
L
P
E
D
A
P
E
D
A
E
P
Q
Red Bread Mold
Neurospora crassa
O74225
707
78655
K527
G
D
K
P
K
T
R
K
V
K
K
Q
V
R
K
Conservation
Percent
Protein Identity:
100
99.2
63.8
95.9
N.A.
92.6
63.3
N.A.
60.1
81.6
28.7
65.7
N.A.
28
N.A.
43
49.6
Protein Similarity:
100
99.4
79.2
98.3
N.A.
96.5
79
N.A.
75.9
91.4
47.2
81.6
N.A.
46.9
N.A.
58.8
67.9
P-Site Identity:
100
100
33.3
86.6
N.A.
86.6
33.3
N.A.
40
66.6
0
33.3
N.A.
0
N.A.
6.6
13.3
P-Site Similarity:
100
100
60
93.3
N.A.
100
60
N.A.
66.6
80
0
80
N.A.
6.6
N.A.
20
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.8
38.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.2
55.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
14
0
0
14
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
14
0
0
7
7
7
0
0
27
60
0
0
0
0
% D
% Glu:
0
20
0
67
0
7
0
0
40
47
14
0
7
0
0
% E
% Phe:
7
0
14
7
0
54
0
0
0
0
7
0
0
0
27
% F
% Gly:
40
7
0
0
7
0
0
7
0
0
0
7
7
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
7
40
0
7
0
0
7
0
0
0
% I
% Lys:
0
7
14
0
67
0
0
7
0
14
7
0
0
34
7
% K
% Leu:
7
0
7
7
0
7
0
0
0
0
0
20
0
0
40
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
47
7
0
% N
% Pro:
7
0
7
7
7
0
7
7
27
14
7
0
7
20
0
% P
% Gln:
0
0
0
0
7
0
7
0
7
0
0
7
0
0
14
% Q
% Arg:
7
0
0
0
0
0
7
0
0
0
7
27
0
20
0
% R
% Ser:
0
0
0
7
7
0
7
27
0
0
0
7
14
20
0
% S
% Thr:
27
0
7
0
0
7
0
40
0
0
0
7
7
0
0
% T
% Val:
0
47
0
7
0
0
27
0
7
0
0
0
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
54
0
0
14
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _