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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPA4L
All Species:
16.36
Human Site:
T816
Identified Species:
25.71
UniProt:
O95757
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95757
NP_055093.2
839
94486
T816
P
M
D
G
Q
S
G
T
E
T
K
S
D
S
T
Chimpanzee
Pan troglodytes
XP_001157094
840
94684
T817
P
M
D
G
Q
S
G
T
E
T
K
S
D
S
T
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
N812
P
V
D
G
Q
G
D
N
P
G
P
Q
A
A
E
Dog
Lupus familis
XP_533297
840
94621
T817
P
M
D
G
Q
S
G
T
E
T
K
A
D
T
T
Cat
Felis silvestris
Mouse
Mus musculus
P48722
838
94364
S816
P
M
D
G
Q
S
G
S
E
T
S
P
D
P
P
Rat
Rattus norvegicus
O88600
840
94038
N812
P
V
D
G
Q
G
D
N
P
G
T
Q
A
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510127
834
93982
N805
P
V
E
G
N
G
E
N
G
Q
E
A
Q
A
A
Chicken
Gallus gallus
NP_001012594
843
94794
T820
P
V
N
G
Q
S
S
T
E
T
G
P
D
P
A
Frog
Xenopus laevis
P02827
647
70897
P625
G
G
V
P
G
G
M
P
G
S
S
C
G
A
Q
Zebra Danio
Brachydanio rerio
XP_690505
826
93290
T803
D
G
A
H
N
G
P
T
A
Q
Q
G
A
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VG58
641
70235
G619
A
G
A
A
G
G
P
G
A
N
C
G
Q
Q
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
P753
K
P
A
A
P
A
P
P
K
K
E
E
P
Q
P
Sea Urchin
Strong. purpuratus
Q06068
889
98600
G853
P
A
P
P
T
T
E
G
G
E
E
K
M
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32590
693
77602
E671
D
I
A
E
K
L
A
E
Q
R
R
A
R
A
A
Red Bread Mold
Neurospora crassa
O74225
707
78655
A685
K
E
A
A
E
K
A
A
Q
E
G
A
K
D
D
Conservation
Percent
Protein Identity:
100
99.2
63.8
95.9
N.A.
92.6
63.3
N.A.
60.1
81.6
28.7
65.7
N.A.
28
N.A.
43
49.6
Protein Similarity:
100
99.4
79.2
98.3
N.A.
96.5
79
N.A.
75.9
91.4
47.2
81.6
N.A.
46.9
N.A.
58.8
67.9
P-Site Identity:
100
100
26.6
86.6
N.A.
66.6
26.6
N.A.
13.3
53.3
0
6.6
N.A.
0
N.A.
0
13.3
P-Site Similarity:
100
100
40
100
N.A.
73.3
40
N.A.
46.6
66.6
13.3
20
N.A.
0
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.8
38.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.2
55.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
34
20
0
7
14
7
14
0
0
27
20
34
27
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% C
% Asp:
14
0
40
0
0
0
14
0
0
0
0
0
34
20
7
% D
% Glu:
0
7
7
7
7
0
14
7
34
14
20
7
0
0
14
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
20
0
54
14
40
27
14
20
14
14
14
7
0
0
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
14
0
0
0
7
7
0
0
7
7
20
7
7
0
0
% K
% Leu:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% L
% Met:
0
27
0
0
0
0
7
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
7
0
14
0
0
20
0
7
0
0
0
0
0
% N
% Pro:
60
7
7
14
7
0
20
14
14
0
7
14
7
14
14
% P
% Gln:
0
0
0
0
47
0
0
0
14
14
7
14
14
14
7
% Q
% Arg:
0
0
0
0
0
0
0
0
0
7
7
0
7
0
0
% R
% Ser:
0
0
0
0
0
34
7
7
0
7
14
14
0
14
7
% S
% Thr:
0
0
0
0
7
7
0
34
0
34
7
0
0
7
27
% T
% Val:
0
27
7
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _