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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPA4L All Species: 15.76
Human Site: T818 Identified Species: 24.76
UniProt: O95757 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95757 NP_055093.2 839 94486 T818 D G Q S G T E T K S D S T K D
Chimpanzee Pan troglodytes XP_001157094 840 94684 T819 D G Q S G T E T K S D S T K D
Rhesus Macaque Macaca mulatta XP_001106968 840 94362 G814 D G Q G D N P G P Q A A E Q G
Dog Lupus familis XP_533297 840 94621 T819 D G Q S G T E T K A D T T K D
Cat Felis silvestris
Mouse Mus musculus P48722 838 94364 T818 D G Q S G S E T S P D P P K G
Rat Rattus norvegicus O88600 840 94038 G814 D G Q G D N P G T Q A A E H G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510127 834 93982 Q807 E G N G E N G Q E A Q A A E Q
Chicken Gallus gallus NP_001012594 843 94794 T822 N G Q S S T E T G P D P A K D
Frog Xenopus laevis P02827 647 70897 S627 V P G G M P G S S C G A Q A R
Zebra Danio Brachydanio rerio XP_690505 826 93290 Q805 A H N G P T A Q Q G A D S K G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VG58 641 70235 N621 A A G G P G A N C G Q Q A G G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q05036 776 86878 K755 A A P A P P K K E E P Q P A A
Sea Urchin Strong. purpuratus Q06068 889 98600 E855 P P T T E G G E E K M D T S D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32590 693 77602 R673 A E K L A E Q R R A R A A S D
Red Bread Mold Neurospora crassa O74225 707 78655 E687 A A E K A A Q E G A K D D E M
Conservation
Percent
Protein Identity: 100 99.2 63.8 95.9 N.A. 92.6 63.3 N.A. 60.1 81.6 28.7 65.7 N.A. 28 N.A. 43 49.6
Protein Similarity: 100 99.4 79.2 98.3 N.A. 96.5 79 N.A. 75.9 91.4 47.2 81.6 N.A. 46.9 N.A. 58.8 67.9
P-Site Identity: 100 100 20 86.6 N.A. 60 20 N.A. 6.6 60 0 13.3 N.A. 0 N.A. 0 13.3
P-Site Similarity: 100 100 33.3 100 N.A. 66.6 26.6 N.A. 40 66.6 13.3 26.6 N.A. 0 N.A. 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.8 38.3
Protein Similarity: N.A. N.A. N.A. N.A. 51.2 55.5
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 0
P-Site Similarity: N.A. N.A. N.A. N.A. 40 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 20 0 7 14 7 14 0 0 27 20 34 27 14 7 % A
% Cys: 0 0 0 0 0 0 0 0 7 7 0 0 0 0 0 % C
% Asp: 40 0 0 0 14 0 0 0 0 0 34 20 7 0 40 % D
% Glu: 7 7 7 0 14 7 34 14 20 7 0 0 14 14 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 54 14 40 27 14 20 14 14 14 7 0 0 7 34 % G
% His: 0 7 0 0 0 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 7 7 0 0 7 7 20 7 7 0 0 40 0 % K
% Leu: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 7 0 0 0 0 0 7 0 0 0 7 % M
% Asn: 7 0 14 0 0 20 0 7 0 0 0 0 0 0 0 % N
% Pro: 7 14 7 0 20 14 14 0 7 14 7 14 14 0 0 % P
% Gln: 0 0 47 0 0 0 14 14 7 14 14 14 7 7 7 % Q
% Arg: 0 0 0 0 0 0 0 7 7 0 7 0 0 0 7 % R
% Ser: 0 0 0 34 7 7 0 7 14 14 0 14 7 14 0 % S
% Thr: 0 0 7 7 0 34 0 34 7 0 0 7 27 0 0 % T
% Val: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _