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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPA4L All Species: 34.24
Human Site: Y105 Identified Species: 53.81
UniProt: O95757 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95757 NP_055093.2 839 94486 Y105 S A G V K V R Y L E E E R P F
Chimpanzee Pan troglodytes XP_001157094 840 94684 Y105 S A G V K V R Y L E E E R P F
Rhesus Macaque Macaca mulatta XP_001106968 840 94362 Y105 L T G I K V T Y M E E E R N F
Dog Lupus familis XP_533297 840 94621 Y105 S A G V K V R Y L E E E R P F
Cat Felis silvestris
Mouse Mus musculus P48722 838 94364 Y105 S T G V K V R Y L E E E R P F
Rat Rattus norvegicus O88600 840 94038 Y105 L T G I K V T Y M E E E R N F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510127 834 93982 T107 M E E E R S F T T E Q V T G M
Chicken Gallus gallus NP_001012594 843 94794 Y105 S V G V K V R Y L D E E R L F
Frog Xenopus laevis P02827 647 70897
Zebra Danio Brachydanio rerio XP_690505 826 93290 Y105 N A G I K V R Y L N E D K V F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VG58 641 70235
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q05036 776 86878 Y105 D I G V Q V S Y L G E P H T F
Sea Urchin Strong. purpuratus Q06068 889 98600 Y105 N V G M Q V Q Y L G E T E T F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32590 693 77602 I24 A V A R N R G I D V V V N E V
Red Bread Mold Neurospora crassa O74225 707 78655 L38 S N R A T P S L V G F G P K S
Conservation
Percent
Protein Identity: 100 99.2 63.8 95.9 N.A. 92.6 63.3 N.A. 60.1 81.6 28.7 65.7 N.A. 28 N.A. 43 49.6
Protein Similarity: 100 99.4 79.2 98.3 N.A. 96.5 79 N.A. 75.9 91.4 47.2 81.6 N.A. 46.9 N.A. 58.8 67.9
P-Site Identity: 100 100 60 100 N.A. 93.3 60 N.A. 6.6 80 0 60 N.A. 0 N.A. 46.6 40
P-Site Similarity: 100 100 73.3 100 N.A. 93.3 73.3 N.A. 20 86.6 0 86.6 N.A. 0 N.A. 53.3 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.8 38.3
Protein Similarity: N.A. N.A. N.A. N.A. 51.2 55.5
P-Site Identity: N.A. N.A. N.A. N.A. 0 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 27 7 7 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 0 0 0 7 7 0 7 0 0 0 % D
% Glu: 0 7 7 7 0 0 0 0 0 47 67 47 7 7 0 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 7 0 0 0 67 % F
% Gly: 0 0 67 0 0 0 7 0 0 20 0 7 0 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % H
% Ile: 0 7 0 20 0 0 0 7 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 54 0 0 0 0 0 0 0 7 7 0 % K
% Leu: 14 0 0 0 0 0 0 7 54 0 0 0 0 7 0 % L
% Met: 7 0 0 7 0 0 0 0 14 0 0 0 0 0 7 % M
% Asn: 14 7 0 0 7 0 0 0 0 7 0 0 7 14 0 % N
% Pro: 0 0 0 0 0 7 0 0 0 0 0 7 7 27 0 % P
% Gln: 0 0 0 0 14 0 7 0 0 0 7 0 0 0 0 % Q
% Arg: 0 0 7 7 7 7 40 0 0 0 0 0 47 0 0 % R
% Ser: 40 0 0 0 0 7 14 0 0 0 0 0 0 0 7 % S
% Thr: 0 20 0 0 7 0 14 7 7 0 0 7 7 14 0 % T
% Val: 0 20 0 40 0 67 0 0 7 7 7 14 0 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 67 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _