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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPA4L
All Species:
35.15
Human Site:
Y252
Identified Species:
55.24
UniProt:
O95757
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95757
NP_055093.2
839
94486
Y252
C
D
E
F
K
T
K
Y
K
I
N
V
K
E
N
Chimpanzee
Pan troglodytes
XP_001157094
840
94684
Y252
C
D
E
F
K
T
K
Y
K
I
N
V
K
E
N
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
Y252
C
E
E
F
G
K
K
Y
K
L
D
I
K
S
K
Dog
Lupus familis
XP_533297
840
94621
Y252
C
E
E
F
K
T
K
Y
K
I
N
V
K
E
N
Cat
Felis silvestris
Mouse
Mus musculus
P48722
838
94364
Y252
C
D
E
F
K
T
K
Y
K
I
N
V
K
E
N
Rat
Rattus norvegicus
O88600
840
94038
Y252
C
E
E
F
G
K
K
Y
K
L
D
I
K
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510127
834
93982
Y246
C
E
E
F
G
K
K
Y
K
L
D
I
K
S
K
Chicken
Gallus gallus
NP_001012594
843
94794
Y252
S
E
E
F
R
T
K
Y
K
L
N
V
K
E
N
Frog
Xenopus laevis
P02827
647
70897
S114
E
Y
K
G
E
E
K
S
F
F
P
E
E
I
S
Zebra Danio
Brachydanio rerio
XP_690505
826
93290
F252
C
E
D
F
K
N
R
F
K
L
N
V
K
D
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VG58
641
70235
S108
G
V
E
Y
K
G
E
S
K
R
F
A
P
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
L241
G
G
I
W
F
D
A
L
I
R
E
H
F
R
K
Sea Urchin
Strong. purpuratus
Q06068
889
98600
Y252
A
V
D
F
Q
T
R
Y
K
M
D
V
K
S
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32590
693
77602
A160
Q
R
Y
N
I
A
D
A
A
R
I
A
G
L
N
Red Bread Mold
Neurospora crassa
O74225
707
78655
T174
L
R
L
I
N
D
T
T
A
A
A
L
G
W
G
Conservation
Percent
Protein Identity:
100
99.2
63.8
95.9
N.A.
92.6
63.3
N.A.
60.1
81.6
28.7
65.7
N.A.
28
N.A.
43
49.6
Protein Similarity:
100
99.4
79.2
98.3
N.A.
96.5
79
N.A.
75.9
91.4
47.2
81.6
N.A.
46.9
N.A.
58.8
67.9
P-Site Identity:
100
100
46.6
93.3
N.A.
100
46.6
N.A.
46.6
73.3
6.6
53.3
N.A.
26.6
N.A.
0
46.6
P-Site Similarity:
100
100
73.3
100
N.A.
100
73.3
N.A.
73.3
93.3
33.3
93.3
N.A.
40
N.A.
6.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.8
38.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.2
55.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
7
7
7
14
7
7
14
0
0
0
% A
% Cys:
54
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
14
0
0
14
7
0
0
0
27
0
0
7
0
% D
% Glu:
7
40
60
0
7
7
7
0
0
0
7
7
7
40
7
% E
% Phe:
0
0
0
67
7
0
0
7
7
7
7
0
7
0
0
% F
% Gly:
14
7
0
7
20
7
0
0
0
0
0
0
14
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
7
7
7
0
0
0
7
27
7
20
0
7
0
% I
% Lys:
0
0
7
0
40
20
60
0
74
0
0
0
67
0
27
% K
% Leu:
7
0
7
0
0
0
0
7
0
34
0
7
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
7
7
7
0
0
0
0
40
0
0
0
54
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% P
% Gln:
7
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
14
0
0
7
0
14
0
0
20
0
0
0
7
0
% R
% Ser:
7
0
0
0
0
0
0
14
0
0
0
0
0
27
7
% S
% Thr:
0
0
0
0
0
40
7
7
0
0
0
0
0
0
0
% T
% Val:
0
14
0
0
0
0
0
0
0
0
0
47
0
0
0
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% W
% Tyr:
0
7
7
7
0
0
0
60
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _