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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPA4L
All Species:
28.79
Human Site:
Y454
Identified Species:
45.24
UniProt:
O95757
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95757
NP_055093.2
839
94486
Y454
T
N
L
H
E
V
P
Y
P
D
A
R
I
G
S
Chimpanzee
Pan troglodytes
XP_001157094
840
94684
Y454
T
N
L
H
E
V
P
Y
P
D
A
R
I
G
S
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
Y454
S
S
P
Q
D
L
P
Y
P
D
P
A
I
A
Q
Dog
Lupus familis
XP_533297
840
94621
Y454
T
N
L
H
E
V
P
Y
P
D
P
R
I
G
S
Cat
Felis silvestris
Mouse
Mus musculus
P48722
838
94364
Y454
T
N
L
H
E
V
P
Y
P
D
P
R
I
G
N
Rat
Rattus norvegicus
O88600
840
94038
Y454
S
S
P
Q
D
L
P
Y
P
D
P
A
I
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510127
834
93982
Y448
G
S
P
K
D
L
P
Y
P
D
P
A
I
A
Q
Chicken
Gallus gallus
NP_001012594
843
94794
Y454
T
H
P
H
E
V
P
Y
P
D
S
R
I
G
R
Frog
Xenopus laevis
P02827
647
70897
R302
Y
T
A
I
T
R
A
R
F
E
E
L
C
S
D
Zebra Danio
Brachydanio rerio
XP_690505
826
93290
Y454
S
C
P
H
D
L
P
Y
P
D
V
R
I
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VG58
641
70235
S296
Q
D
F
Y
T
K
V
S
R
A
R
F
E
E
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
P429
F
S
P
R
D
E
V
P
F
S
K
L
V
S
L
Sea Urchin
Strong. purpuratus
Q06068
889
98600
I452
Y
A
D
P
N
L
P
I
P
E
R
R
I
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32590
693
77602
P348
I
G
G
T
T
R
I
P
V
L
K
K
S
I
S
Red Bread Mold
Neurospora crassa
O74225
707
78655
F362
F
F
G
K
Q
L
S
F
T
M
N
Q
D
E
A
Conservation
Percent
Protein Identity:
100
99.2
63.8
95.9
N.A.
92.6
63.3
N.A.
60.1
81.6
28.7
65.7
N.A.
28
N.A.
43
49.6
Protein Similarity:
100
99.4
79.2
98.3
N.A.
96.5
79
N.A.
75.9
91.4
47.2
81.6
N.A.
46.9
N.A.
58.8
67.9
P-Site Identity:
100
100
33.3
93.3
N.A.
86.6
33.3
N.A.
33.3
73.3
0
53.3
N.A.
0
N.A.
0
33.3
P-Site Similarity:
100
100
60
93.3
N.A.
93.3
60
N.A.
53.3
86.6
6.6
73.3
N.A.
13.3
N.A.
20
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.8
38.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.2
55.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
0
7
0
0
7
14
20
0
20
7
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
0
7
7
0
34
0
0
0
0
60
0
0
7
0
7
% D
% Glu:
0
0
0
0
34
7
0
0
0
14
7
0
7
14
0
% E
% Phe:
14
7
7
0
0
0
0
7
14
0
0
7
0
0
0
% F
% Gly:
7
7
14
0
0
0
0
0
0
0
0
0
0
47
0
% G
% His:
0
7
0
40
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
7
0
0
7
7
0
0
0
0
67
7
0
% I
% Lys:
0
0
0
14
0
7
0
0
0
0
14
7
0
0
0
% K
% Leu:
0
0
27
0
0
40
0
0
0
7
0
14
0
0
14
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
27
0
0
7
0
0
0
0
0
7
0
0
0
7
% N
% Pro:
0
0
40
7
0
0
67
14
67
0
34
0
0
0
0
% P
% Gln:
7
0
0
14
7
0
0
0
0
0
0
7
0
0
20
% Q
% Arg:
0
0
0
7
0
14
0
7
7
0
14
47
0
0
20
% R
% Ser:
20
27
0
0
0
0
7
7
0
7
7
0
7
14
27
% S
% Thr:
34
7
0
7
20
0
0
0
7
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
34
14
0
7
0
7
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
14
0
0
7
0
0
0
60
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _