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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPA4L
All Species:
31.21
Human Site:
Y600
Identified Species:
49.05
UniProt:
O95757
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95757
NP_055093.2
839
94486
Y600
G
Q
D
L
L
N
S
Y
I
E
N
E
G
K
M
Chimpanzee
Pan troglodytes
XP_001157094
840
94684
Y601
G
Q
D
L
L
N
S
Y
I
E
N
E
G
K
M
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
Y597
D
R
E
M
L
N
L
Y
I
E
N
E
G
K
M
Dog
Lupus familis
XP_533297
840
94621
Y601
G
Q
D
L
L
N
S
Y
I
E
N
E
G
K
M
Cat
Felis silvestris
Mouse
Mus musculus
P48722
838
94364
Y600
T
Q
D
L
L
N
S
Y
I
E
N
E
G
K
M
Rat
Rattus norvegicus
O88600
840
94038
Y597
D
R
E
M
L
G
L
Y
T
E
N
E
G
K
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510127
834
93982
Y591
G
R
D
M
L
N
L
Y
I
E
N
E
G
K
M
Chicken
Gallus gallus
NP_001012594
843
94794
Y603
G
Q
D
L
I
N
C
Y
I
E
N
E
G
K
M
Frog
Xenopus laevis
P02827
647
70897
N435
S
F
T
T
Y
S
D
N
Q
P
G
V
L
I
Q
Zebra Danio
Brachydanio rerio
XP_690505
826
93290
F592
D
R
D
V
L
T
H
F
V
E
Y
E
K
K
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VG58
641
70235
Y429
Q
T
K
T
F
S
T
Y
S
D
N
Q
P
G
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
M563
F
H
N
L
E
L
Q
M
Q
E
S
D
A
R
E
Sea Urchin
Strong. purpuratus
Q06068
889
98600
G588
S
K
D
Q
N
S
E
G
S
K
S
D
N
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32590
693
77602
K481
D
F
I
P
V
K
V
K
L
R
C
D
P
S
G
Red Bread Mold
Neurospora crassa
O74225
707
78655
E495
I
H
G
I
L
N
V
E
S
A
Y
Y
V
E
D
Conservation
Percent
Protein Identity:
100
99.2
63.8
95.9
N.A.
92.6
63.3
N.A.
60.1
81.6
28.7
65.7
N.A.
28
N.A.
43
49.6
Protein Similarity:
100
99.4
79.2
98.3
N.A.
96.5
79
N.A.
75.9
91.4
47.2
81.6
N.A.
46.9
N.A.
58.8
67.9
P-Site Identity:
100
100
66.6
100
N.A.
93.3
53.3
N.A.
80
86.6
0
40
N.A.
13.3
N.A.
13.3
6.6
P-Site Similarity:
100
100
86.6
100
N.A.
93.3
73.3
N.A.
93.3
93.3
6.6
66.6
N.A.
46.6
N.A.
40
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.8
38.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.2
55.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% C
% Asp:
27
0
54
0
0
0
7
0
0
7
0
20
0
0
7
% D
% Glu:
0
0
14
0
7
0
7
7
0
67
0
60
0
7
7
% E
% Phe:
7
14
0
0
7
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
34
0
7
0
0
7
0
7
0
0
7
0
54
7
7
% G
% His:
0
14
0
0
0
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
7
7
7
0
0
0
47
0
0
0
0
7
0
% I
% Lys:
0
7
7
0
0
7
0
7
0
7
0
0
7
60
0
% K
% Leu:
0
0
0
40
60
7
20
0
7
0
0
0
7
0
0
% L
% Met:
0
0
0
20
0
0
0
7
0
0
0
0
0
0
60
% M
% Asn:
0
0
7
0
7
54
0
7
0
0
60
0
7
0
0
% N
% Pro:
0
0
0
7
0
0
0
0
0
7
0
0
14
0
0
% P
% Gln:
7
34
0
7
0
0
7
0
14
0
0
7
0
0
7
% Q
% Arg:
0
27
0
0
0
0
0
0
0
7
0
0
0
7
0
% R
% Ser:
14
0
0
0
0
20
27
0
20
0
14
0
0
14
7
% S
% Thr:
7
7
7
14
0
7
7
0
7
0
0
0
0
0
0
% T
% Val:
0
0
0
7
7
0
14
0
7
0
0
7
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
60
0
0
14
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _