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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPA4L All Species: 18.48
Human Site: Y684 Identified Species: 29.05
UniProt: O95757 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95757 NP_055093.2 839 94486 Y684 K L Q E L K K Y G Q P I Q M K
Chimpanzee Pan troglodytes XP_001157094 840 94684 Y685 K L Q E L K K Y G Q P I Q M K
Rhesus Macaque Macaca mulatta XP_001106968 840 94362 L681 K L A E L K N L G Q P I K I R
Dog Lupus familis XP_533297 840 94621 Y685 K L Q E L K K Y G Q P I Q M R
Cat Felis silvestris
Mouse Mus musculus P48722 838 94364 Y684 R L Q E L K K Y G Q P I Q M K
Rat Rattus norvegicus O88600 840 94038 L681 K L A E L R T L G Q P I K T R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510127 834 93982 L675 K L T E L K N L G Q P I K A R
Chicken Gallus gallus NP_001012594 843 94794 F687 K L Q E L R K F G Q P I Q E R
Frog Xenopus laevis P02827 647 70897 D507 N K I T I T N D K G R L S K E
Zebra Danio Brachydanio rerio XP_690505 826 93290 Y676 K L A E L K K Y G E P I E E R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VG58 641 70235 I501 G K A K N I T I K N D K G R L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q05036 776 86878 S635 D V Y E K R L S E L K A V G T
Sea Urchin Strong. purpuratus Q06068 889 98600 I716 K I N S L K K I G D P V E N R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32590 693 77602 K553 E L N D L I E K E N E L R N Q
Red Bread Mold Neurospora crassa O74225 707 78655 L567 A M I M E D K L V A D T E E K
Conservation
Percent
Protein Identity: 100 99.2 63.8 95.9 N.A. 92.6 63.3 N.A. 60.1 81.6 28.7 65.7 N.A. 28 N.A. 43 49.6
Protein Similarity: 100 99.4 79.2 98.3 N.A. 96.5 79 N.A. 75.9 91.4 47.2 81.6 N.A. 46.9 N.A. 58.8 67.9
P-Site Identity: 100 100 60 93.3 N.A. 93.3 53.3 N.A. 60 73.3 0 66.6 N.A. 0 N.A. 6.6 40
P-Site Similarity: 100 100 80 100 N.A. 100 73.3 N.A. 73.3 93.3 20 86.6 N.A. 6.6 N.A. 20 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.8 38.3
Protein Similarity: N.A. N.A. N.A. N.A. 51.2 55.5
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 53.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 27 0 0 0 0 0 0 7 0 7 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 7 0 7 0 7 0 7 14 0 0 0 0 % D
% Glu: 7 0 0 67 7 0 7 0 14 7 7 0 20 20 7 % E
% Phe: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % F
% Gly: 7 0 0 0 0 0 0 0 67 7 0 0 7 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 14 0 7 14 0 14 0 0 0 60 0 7 0 % I
% Lys: 60 14 0 7 7 54 54 7 14 0 7 7 20 7 27 % K
% Leu: 0 67 0 0 74 0 7 27 0 7 0 14 0 0 7 % L
% Met: 0 7 0 7 0 0 0 0 0 0 0 0 0 27 0 % M
% Asn: 7 0 14 0 7 0 20 0 0 14 0 0 0 14 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 67 0 0 0 0 % P
% Gln: 0 0 34 0 0 0 0 0 0 54 0 0 34 0 7 % Q
% Arg: 7 0 0 0 0 20 0 0 0 0 7 0 7 7 47 % R
% Ser: 0 0 0 7 0 0 0 7 0 0 0 0 7 0 0 % S
% Thr: 0 0 7 7 0 7 14 0 0 0 0 7 0 7 7 % T
% Val: 0 7 0 0 0 0 0 0 7 0 0 7 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 34 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _