KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP2A1
All Species:
42.42
Human Site:
S238
Identified Species:
84.85
UniProt:
O95782
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95782
NP_570603.2
977
107546
S238
S
R
L
S
R
I
V
S
S
A
S
T
D
L
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001115458
977
107553
S238
S
R
L
S
R
I
V
S
S
A
S
T
D
L
Q
Dog
Lupus familis
XP_541490
922
101289
T227
R
L
V
E
C
L
E
T
V
L
N
K
A
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
P17426
977
107646
S238
S
R
L
S
R
I
V
S
S
A
S
T
D
L
Q
Rat
Rattus norvegicus
P18484
938
104026
T238
S
R
L
S
R
I
V
T
S
A
S
T
D
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012914
938
104174
T238
S
R
L
S
R
I
V
T
S
A
S
T
D
L
Q
Frog
Xenopus laevis
NP_001089303
939
104392
T238
S
R
L
S
R
I
V
T
S
A
A
T
D
L
Q
Zebra Danio
Brachydanio rerio
XP_001922441
959
106027
S238
S
R
L
S
R
I
V
S
S
A
S
T
D
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91926
940
105602
T237
S
R
L
S
R
I
V
T
A
S
Y
T
D
L
Q
Honey Bee
Apis mellifera
XP_394621
937
104937
T237
S
R
L
S
R
I
V
T
S
S
Y
T
D
L
Q
Nematode Worm
Caenorhab. elegans
NP_509572
925
104161
T237
S
R
L
S
R
I
V
T
A
T
Y
T
D
L
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38065
1025
114993
S279
V
V
V
G
T
S
R
S
S
D
N
Q
F
P
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.5
91.3
N.A.
98.4
79.4
N.A.
N.A.
79.5
78.3
82.1
N.A.
66.6
68
62.2
N.A.
Protein Similarity:
100
N.A.
99.8
92.7
N.A.
98.8
86.9
N.A.
N.A.
87.4
87
88.1
N.A.
77.8
78.8
74.9
N.A.
P-Site Identity:
100
N.A.
100
0
N.A.
100
93.3
N.A.
N.A.
93.3
86.6
100
N.A.
73.3
80
73.3
N.A.
P-Site Similarity:
100
N.A.
100
33.3
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
93.3
93.3
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
17
59
9
0
9
0
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
9
0
0
84
0
0
% D
% Glu:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
84
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% K
% Leu:
0
9
84
0
0
9
0
0
0
9
0
0
0
84
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
84
% Q
% Arg:
9
84
0
0
84
0
9
0
0
0
0
0
0
0
0
% R
% Ser:
84
0
0
84
0
9
0
42
75
17
50
0
0
0
0
% S
% Thr:
0
0
0
0
9
0
0
59
0
9
0
84
0
0
0
% T
% Val:
9
9
17
0
0
0
84
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
25
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _