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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP2A1
All Species:
41.52
Human Site:
Y53
Identified Species:
83.03
UniProt:
O95782
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95782
NP_570603.2
977
107546
Y53
G
D
K
A
L
D
G
Y
S
K
K
K
Y
V
C
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001115458
977
107553
Y53
G
D
K
A
L
D
G
Y
S
K
K
K
Y
V
C
Dog
Lupus familis
XP_541490
922
101289
N55
E
L
I
R
L
I
N
N
A
I
K
N
D
L
A
Cat
Felis silvestris
Mouse
Mus musculus
P17426
977
107646
Y53
G
D
K
A
L
D
G
Y
S
K
K
K
Y
V
C
Rat
Rattus norvegicus
P18484
938
104026
Y53
G
D
K
A
L
D
G
Y
S
K
K
K
Y
V
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012914
938
104174
Y53
G
D
K
A
L
D
G
Y
S
K
K
K
Y
V
C
Frog
Xenopus laevis
NP_001089303
939
104392
Y53
G
D
K
A
L
D
G
Y
S
K
K
K
Y
V
C
Zebra Danio
Brachydanio rerio
XP_001922441
959
106027
Y53
G
D
K
A
L
D
G
Y
S
K
K
K
Y
V
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91926
940
105602
Y52
G
D
K
T
L
D
G
Y
Q
K
K
K
Y
V
C
Honey Bee
Apis mellifera
XP_394621
937
104937
Y52
G
D
K
T
L
D
G
Y
Q
K
K
K
Y
V
C
Nematode Worm
Caenorhab. elegans
NP_509572
925
104161
Y52
G
D
K
T
L
D
G
Y
Q
K
K
K
Y
V
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38065
1025
114993
Y69
N
H
D
R
L
G
G
Y
Q
R
K
K
Y
V
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.5
91.3
N.A.
98.4
79.4
N.A.
N.A.
79.5
78.3
82.1
N.A.
66.6
68
62.2
N.A.
Protein Similarity:
100
N.A.
99.8
92.7
N.A.
98.8
86.9
N.A.
N.A.
87.4
87
88.1
N.A.
77.8
78.8
74.9
N.A.
P-Site Identity:
100
N.A.
100
13.3
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
86.6
86.6
86.6
N.A.
P-Site Similarity:
100
N.A.
100
26.6
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
86.6
86.6
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
59
0
0
0
0
9
0
0
0
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
84
% C
% Asp:
0
84
9
0
0
84
0
0
0
0
0
0
9
0
0
% D
% Glu:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
84
0
0
0
0
9
92
0
0
0
0
0
0
0
0
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
9
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
0
84
0
0
0
0
0
0
84
100
92
0
0
0
% K
% Leu:
0
9
0
0
100
0
0
0
0
0
0
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
9
9
0
0
0
9
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
34
0
0
0
0
0
0
% Q
% Arg:
0
0
0
17
0
0
0
0
0
9
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
59
0
0
0
0
0
0
% S
% Thr:
0
0
0
25
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
92
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
92
0
0
0
0
92
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _