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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP2A1
All Species:
33.64
Human Site:
Y780
Identified Species:
67.27
UniProt:
O95782
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95782
NP_570603.2
977
107546
Y780
L
G
R
M
Y
L
F
Y
G
N
K
T
S
V
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001115458
977
107553
Y780
L
G
R
M
Y
L
F
Y
G
N
K
T
S
V
Q
Dog
Lupus familis
XP_541490
922
101289
Y722
L
G
R
M
Y
L
F
Y
G
N
K
T
S
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
P17426
977
107646
Y780
L
G
R
M
Y
L
F
Y
G
N
K
T
S
V
Q
Rat
Rattus norvegicus
P18484
938
104026
Y741
L
G
R
M
F
I
F
Y
G
N
K
T
S
T
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012914
938
104174
Y741
L
G
R
M
F
I
F
Y
G
N
K
T
S
T
Q
Frog
Xenopus laevis
NP_001089303
939
104392
F742
L
G
R
M
F
I
F
F
G
N
K
M
S
S
Q
Zebra Danio
Brachydanio rerio
XP_001922441
959
106027
Y762
L
G
R
M
Y
L
F
Y
G
N
K
T
S
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91926
940
105602
Y743
L
G
R
L
G
L
F
Y
G
N
K
T
Q
V
P
Honey Bee
Apis mellifera
XP_394621
937
104937
Y739
L
G
R
V
G
L
F
Y
G
N
K
T
Q
Y
A
Nematode Worm
Caenorhab. elegans
NP_509572
925
104161
C740
K
F
T
P
I
I
T
C
P
G
A
L
A
V
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38065
1025
114993
I816
I
T
G
L
S
T
Q
I
I
P
S
K
T
Q
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.5
91.3
N.A.
98.4
79.4
N.A.
N.A.
79.5
78.3
82.1
N.A.
66.6
68
62.2
N.A.
Protein Similarity:
100
N.A.
99.8
92.7
N.A.
98.8
86.9
N.A.
N.A.
87.4
87
88.1
N.A.
77.8
78.8
74.9
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
80
N.A.
N.A.
80
66.6
100
N.A.
73.3
66.6
13.3
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
93.3
N.A.
N.A.
93.3
86.6
100
N.A.
80
73.3
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
9
0
0
25
0
84
9
0
0
0
0
0
0
0
% F
% Gly:
0
84
9
0
17
0
0
0
84
9
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
9
34
0
9
9
0
0
0
0
0
0
% I
% Lys:
9
0
0
0
0
0
0
0
0
0
84
9
0
0
0
% K
% Leu:
84
0
0
17
0
59
0
0
0
0
0
9
0
0
0
% L
% Met:
0
0
0
67
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
84
0
0
0
0
0
% N
% Pro:
0
0
0
9
0
0
0
0
9
9
0
0
0
0
9
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
0
0
17
9
75
% Q
% Arg:
0
0
84
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
9
0
0
0
0
0
9
0
67
9
0
% S
% Thr:
0
9
9
0
0
9
9
0
0
0
0
75
9
17
0
% T
% Val:
0
0
0
9
0
0
0
0
0
0
0
0
0
59
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
42
0
0
75
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _