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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WIZ All Species: 9.09
Human Site: S1134 Identified Species: 40
UniProt: O95785 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95785 NP_067064.2 1651 178674 S1134 S P S D L H I S P L A K K L P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533888 1889 203336 S1372 S P A D L H L S P L A K K L P
Cat Felis silvestris
Mouse Mus musculus O88286 1684 184273 S1167 S P S D L H I S P L T K K L P
Rat Rattus norvegicus NP_001101534 962 103626 P534 N L S S R A E P V R D I R C E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518622 833 90580 S405 M S P L N L S S R A E P V R D
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001341794 1357 147992 I929 E P G Q D G R I S L S S P G Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 78.7 N.A. 82.4 54.4 N.A. 40.5 N.A. N.A. 23.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. N.A. 81.4 N.A. 87.5 55.6 N.A. 44 N.A. N.A. 36.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. N.A. 86.6 N.A. 93.3 6.6 N.A. 6.6 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. N.A. 100 N.A. 93.3 20 N.A. 6.6 N.A. N.A. 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 0 0 17 0 0 0 17 34 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % C
% Asp: 0 0 0 50 17 0 0 0 0 0 17 0 0 0 17 % D
% Glu: 17 0 0 0 0 0 17 0 0 0 17 0 0 0 17 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 17 0 0 17 0 0 0 0 0 0 0 17 0 % G
% His: 0 0 0 0 0 50 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 34 17 0 0 0 17 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 50 50 0 0 % K
% Leu: 0 17 0 17 50 17 17 0 0 67 0 0 0 50 0 % L
% Met: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 17 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 67 17 0 0 0 0 17 50 0 0 17 17 0 50 % P
% Gln: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 17 0 17 0 17 17 0 0 17 17 0 % R
% Ser: 50 17 50 17 0 0 17 67 17 0 17 17 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 17 0 0 0 17 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _