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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX58
All Species:
9.7
Human Site:
S223
Identified Species:
23.7
UniProt:
O95786
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95786
NP_055129.2
925
106600
S223
D
P
E
C
Q
N
L
S
E
N
S
C
P
P
S
Chimpanzee
Pan troglodytes
XP_520524
875
100513
N209
L
P
A
M
K
G
K
N
T
I
I
C
A
P
T
Rhesus Macaque
Macaca mulatta
NP_001036133
925
106542
S223
D
P
E
C
Q
N
L
S
E
N
S
C
L
P
S
Dog
Lupus familis
XP_545493
1029
116917
G289
G
S
D
S
G
T
M
G
S
D
S
D
E
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q6Q899
926
105860
S224
E
P
E
C
Q
N
L
S
Q
N
P
G
P
P
S
Rat
Rattus norvegicus
NP_001100115
598
68344
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509166
910
103405
F208
E
E
P
E
K
Q
N
F
S
E
T
L
F
S
S
Chicken
Gallus gallus
XP_422031
1285
144686
T565
N
L
G
Q
S
S
T
T
S
D
S
G
E
D
E
Frog
Xenopus laevis
NP_001085915
682
79226
I22
L
E
G
K
N
I
I
I
W
L
P
T
G
A
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780474
968
110474
D221
G
A
D
D
E
V
D
D
G
H
S
N
G
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.5
95.7
29.9
N.A.
76.6
50
N.A.
54.5
22.2
26.3
N.A.
N.A.
N.A.
N.A.
N.A.
29.5
Protein Similarity:
100
94.5
97.7
45.7
N.A.
86.3
56.7
N.A.
70.5
38.1
40.8
N.A.
N.A.
N.A.
N.A.
N.A.
47.9
P-Site Identity:
100
20
93.3
6.6
N.A.
73.3
0
N.A.
6.6
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
40
93.3
33.3
N.A.
86.6
0
N.A.
26.6
33.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
0
0
0
0
0
0
0
10
10
0
% A
% Cys:
0
0
0
30
0
0
0
0
0
0
0
30
0
0
0
% C
% Asp:
20
0
20
10
0
0
10
10
0
20
0
10
0
10
0
% D
% Glu:
20
20
30
10
10
0
0
0
20
10
0
0
20
10
10
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% F
% Gly:
20
0
20
0
10
10
0
10
10
0
0
20
20
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
10
10
0
10
10
0
0
0
0
% I
% Lys:
0
0
0
10
20
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
20
10
0
0
0
0
30
0
0
10
0
10
10
0
0
% L
% Met:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
10
30
10
10
0
30
0
10
0
0
10
% N
% Pro:
0
40
10
0
0
0
0
0
0
0
20
0
20
40
0
% P
% Gln:
0
0
0
10
30
10
0
0
10
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
0
10
0
10
10
10
0
30
30
0
50
0
0
10
40
% S
% Thr:
0
0
0
0
0
10
10
10
10
0
10
10
0
0
10
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _