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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX58
All Species:
19.39
Human Site:
Y246
Identified Species:
47.41
UniProt:
O95786
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95786
NP_055129.2
925
106600
Y246
S
P
F
K
P
R
N
Y
Q
L
E
L
A
L
P
Chimpanzee
Pan troglodytes
XP_520524
875
100513
L232
L
L
I
C
E
H
H
L
K
K
F
P
Q
G
Q
Rhesus Macaque
Macaca mulatta
NP_001036133
925
106542
Y246
S
P
F
K
L
R
N
Y
Q
L
E
L
A
L
P
Dog
Lupus familis
XP_545493
1029
116917
Y312
P
E
L
H
L
R
P
Y
Q
M
E
V
A
Q
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6Q899
926
105860
Y247
S
P
L
K
P
R
N
Y
Q
L
E
L
A
L
P
Rat
Rattus norvegicus
NP_001100115
598
68344
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509166
910
103405
Y231
S
P
Q
N
A
R
S
Y
Q
M
E
L
A
K
P
Chicken
Gallus gallus
XP_422031
1285
144686
Y588
P
D
L
T
L
R
D
Y
Q
M
E
V
A
K
P
Frog
Xenopus laevis
NP_001085915
682
79226
K45
A
M
R
H
L
E
M
K
R
N
A
K
V
C
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780474
968
110474
Y244
E
E
L
E
L
R
D
Y
Q
E
E
V
L
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.5
95.7
29.9
N.A.
76.6
50
N.A.
54.5
22.2
26.3
N.A.
N.A.
N.A.
N.A.
N.A.
29.5
Protein Similarity:
100
94.5
97.7
45.7
N.A.
86.3
56.7
N.A.
70.5
38.1
40.8
N.A.
N.A.
N.A.
N.A.
N.A.
47.9
P-Site Identity:
100
0
93.3
40
N.A.
93.3
0
N.A.
60
40
0
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
13.3
93.3
53.3
N.A.
93.3
0
N.A.
73.3
60
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
0
0
0
0
10
0
60
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
10
0
0
0
0
20
0
0
0
0
0
0
0
0
% D
% Glu:
10
20
0
10
10
10
0
0
0
10
70
0
0
0
0
% E
% Phe:
0
0
20
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
20
0
10
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
30
0
0
0
10
10
10
0
10
0
20
0
% K
% Leu:
10
10
40
0
50
0
0
10
0
30
0
40
10
30
10
% L
% Met:
0
10
0
0
0
0
10
0
0
30
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
30
0
0
10
0
0
0
0
0
% N
% Pro:
20
40
0
0
20
0
10
0
0
0
0
10
0
0
70
% P
% Gln:
0
0
10
0
0
0
0
0
70
0
0
0
10
10
10
% Q
% Arg:
0
0
10
0
0
70
0
0
10
0
0
0
0
0
0
% R
% Ser:
40
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
30
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _