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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX58
All Species:
16.36
Human Site:
Y566
Identified Species:
40
UniProt:
O95786
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95786
NP_055129.2
925
106600
Y566
R
M
K
D
A
L
D
Y
L
K
D
F
F
S
N
Chimpanzee
Pan troglodytes
XP_520524
875
100513
E533
A
A
G
F
D
E
I
E
Q
D
L
T
Q
R
F
Rhesus Macaque
Macaca mulatta
NP_001036133
925
106542
Y566
R
L
K
D
A
L
D
Y
L
K
D
F
F
S
N
Dog
Lupus familis
XP_545493
1029
116917
G659
D
G
D
G
D
G
D
G
D
E
A
E
D
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6Q899
926
105860
Y567
Q
M
T
D
A
L
N
Y
L
K
A
F
F
H
D
Rat
Rattus norvegicus
NP_001100115
598
68344
T261
P
A
K
K
G
K
N
T
V
I
C
A
P
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509166
910
103405
Y551
R
T
T
D
A
L
D
Y
L
E
D
F
F
N
H
Chicken
Gallus gallus
XP_422031
1285
144686
E921
T
A
E
S
D
D
D
E
E
P
L
V
S
K
Q
Frog
Xenopus laevis
NP_001085915
682
79226
Q345
A
R
L
L
E
L
A
Q
D
V
R
F
E
N
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780474
968
110474
Y569
R
T
S
D
A
I
S
Y
M
E
D
Y
I
N
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.5
95.7
29.9
N.A.
76.6
50
N.A.
54.5
22.2
26.3
N.A.
N.A.
N.A.
N.A.
N.A.
29.5
Protein Similarity:
100
94.5
97.7
45.7
N.A.
86.3
56.7
N.A.
70.5
38.1
40.8
N.A.
N.A.
N.A.
N.A.
N.A.
47.9
P-Site Identity:
100
0
93.3
6.6
N.A.
60
6.6
N.A.
66.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
0
100
13.3
N.A.
80
26.6
N.A.
86.6
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
30
0
0
50
0
10
0
0
0
20
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
10
0
10
50
30
10
50
0
20
10
40
0
10
10
10
% D
% Glu:
0
0
10
0
10
10
0
20
10
30
0
10
10
0
20
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
50
40
0
10
% F
% Gly:
0
10
10
10
10
10
0
10
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% H
% Ile:
0
0
0
0
0
10
10
0
0
10
0
0
10
0
0
% I
% Lys:
0
0
30
10
0
10
0
0
0
30
0
0
0
10
0
% K
% Leu:
0
10
10
10
0
50
0
0
40
0
20
0
0
0
0
% L
% Met:
0
20
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
20
0
0
0
0
0
0
30
20
% N
% Pro:
10
0
0
0
0
0
0
0
0
10
0
0
10
0
10
% P
% Gln:
10
0
0
0
0
0
0
10
10
0
0
0
10
0
10
% Q
% Arg:
40
10
0
0
0
0
0
0
0
0
10
0
0
10
0
% R
% Ser:
0
0
10
10
0
0
10
0
0
0
0
0
10
20
0
% S
% Thr:
10
20
20
0
0
0
0
10
0
0
0
10
0
10
0
% T
% Val:
0
0
0
0
0
0
0
0
10
10
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _