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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX58
All Species:
4.55
Human Site:
Y756
Identified Species:
11.11
UniProt:
O95786
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95786
NP_055129.2
925
106600
Y756
E
K
E
Q
I
N
M
Y
K
E
K
M
M
N
D
Chimpanzee
Pan troglodytes
XP_520524
875
100513
L716
K
M
M
N
D
S
I
L
R
L
Q
T
W
D
E
Rhesus Macaque
Macaca mulatta
NP_001036133
925
106542
Y756
E
K
E
Q
I
N
M
Y
K
E
K
M
M
N
D
Dog
Lupus familis
XP_545493
1029
116917
F852
E
R
E
I
V
N
D
F
R
E
K
M
M
Y
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6Q899
926
105860
I757
E
K
E
K
A
N
M
I
K
E
K
I
M
N
E
Rat
Rattus norvegicus
NP_001100115
598
68344
R444
A
S
V
I
A
T
V
R
D
N
V
E
E
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509166
910
103405
I741
E
R
E
K
T
N
M
I
Q
E
V
M
M
N
E
Chicken
Gallus gallus
XP_422031
1285
144686
F1107
E
R
E
D
V
N
I
F
R
E
N
M
M
Y
K
Frog
Xenopus laevis
NP_001085915
682
79226
L528
Y
Q
K
K
I
K
E
L
Q
E
E
S
V
I
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780474
968
110474
N755
L
Q
D
R
E
L
K
N
I
I
R
V
E
M
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.5
95.7
29.9
N.A.
76.6
50
N.A.
54.5
22.2
26.3
N.A.
N.A.
N.A.
N.A.
N.A.
29.5
Protein Similarity:
100
94.5
97.7
45.7
N.A.
86.3
56.7
N.A.
70.5
38.1
40.8
N.A.
N.A.
N.A.
N.A.
N.A.
47.9
P-Site Identity:
100
0
100
46.6
N.A.
66.6
0
N.A.
53.3
40
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
46.6
100
73.3
N.A.
86.6
13.3
N.A.
80
73.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
20
0
0
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
10
0
10
0
10
0
0
0
0
10
20
% D
% Glu:
60
0
60
0
10
0
10
0
0
70
10
10
20
0
40
% E
% Phe:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
20
30
0
20
20
10
10
0
10
0
10
0
% I
% Lys:
10
30
10
30
0
10
10
0
30
0
40
0
0
0
20
% K
% Leu:
10
0
0
0
0
10
0
20
0
10
0
0
0
10
0
% L
% Met:
0
10
10
0
0
0
40
0
0
0
0
50
60
10
10
% M
% Asn:
0
0
0
10
0
60
0
10
0
10
10
0
0
40
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
20
0
20
0
0
0
0
20
0
10
0
0
0
0
% Q
% Arg:
0
30
0
10
0
0
0
10
30
0
10
0
0
0
0
% R
% Ser:
0
10
0
0
0
10
0
0
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
10
10
0
0
0
0
0
10
0
0
0
% T
% Val:
0
0
10
0
20
0
10
0
0
0
20
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
10
0
0
0
0
0
0
20
0
0
0
0
0
20
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _