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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTC4 All Species: 12.42
Human Site: S267 Identified Species: 18.22
UniProt: O95801 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95801 NP_004614.3 387 44679 S267 N P H G A R L S L D G Q G R L
Chimpanzee Pan troglodytes XP_001153260 387 44743 S267 N P H G A R L S L D D Q G R L
Rhesus Macaque Macaca mulatta XP_001114145 387 44737 S267 N P H G A R L S L D D Q G R L
Dog Lupus familis XP_853176 358 40916 N238 N P Y G A R L N V D E Q G R L
Cat Felis silvestris
Mouse Mus musculus Q8R3H9 386 44320 L233 I K A R N I R L V S E S A G E
Rat Rattus norvegicus NP_001013232 237 27309 I118 A D P D L N A I L Y T N R A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519382 216 24029 D97 L A A G E K E D D E E E E D E
Chicken Gallus gallus XP_426665 313 35720 K191 K L K E R N I K L V V E P S S
Frog Xenopus laevis NP_001085211 384 44859 Y262 N A T G A Q V Y L D E N G R L
Zebra Danio Brachydanio rerio NP_001002122 402 46052 M279 A T G A R V Y M D E Q G V L H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_525106 396 46888 L275 L E D H P V H L D E D G S T L
Honey Bee Apis mellifera XP_624121 332 39077 S205 K I I L H L K S Q A I A A R I
Nematode Worm Caenorhab. elegans NP_495087 419 49032 K297 M H S H E C V K F D D D L N L
Sea Urchin Strong. purpuratus XP_791465 364 41863 P243 N L R F L S D P V D G E D G D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P33313 385 44094 D260 I R L E D P M D F E S Q L I Y
Red Bread Mold Neurospora crassa P23231 624 69413 Q403 D F N K A I E Q N A E D P D I
Conservation
Percent
Protein Identity: 100 98.1 97.1 80.8 N.A. 82.4 53.2 N.A. 32 50.9 59.6 57.4 N.A. 31.3 36.6 30.7 42.1
Protein Similarity: 100 98.7 98.7 87.8 N.A. 90.4 57.8 N.A. 40 64.3 76.7 74.1 N.A. 51 55 47.9 61.5
P-Site Identity: 100 93.3 93.3 73.3 N.A. 0 6.6 N.A. 6.6 6.6 53.3 0 N.A. 6.6 13.3 13.3 20
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 6.6 6.6 N.A. 26.6 20 66.6 6.6 N.A. 13.3 20 20 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.7 20.3
Protein Similarity: N.A. N.A. N.A. N.A. 43.9 34.9
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 20 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 13 13 7 38 0 7 0 0 13 0 7 13 7 7 % A
% Cys: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 7 7 7 7 0 7 13 19 44 25 13 7 13 7 % D
% Glu: 0 7 0 13 13 0 13 0 0 25 32 19 7 0 13 % E
% Phe: 0 7 0 7 0 0 0 0 13 0 0 0 0 0 0 % F
% Gly: 0 0 7 38 0 0 0 0 0 0 13 13 32 13 0 % G
% His: 0 7 19 13 7 0 7 0 0 0 0 0 0 0 7 % H
% Ile: 13 7 7 0 0 13 7 7 0 0 7 0 0 7 13 % I
% Lys: 13 7 7 7 0 7 7 13 0 0 0 0 0 0 0 % K
% Leu: 13 13 7 7 13 7 25 13 38 0 0 0 13 7 44 % L
% Met: 7 0 0 0 0 0 7 7 0 0 0 0 0 0 0 % M
% Asn: 38 0 7 0 7 13 0 7 7 0 0 13 0 7 0 % N
% Pro: 0 25 7 0 7 7 0 7 0 0 0 0 13 0 0 % P
% Gln: 0 0 0 0 0 7 0 7 7 0 7 32 0 0 0 % Q
% Arg: 0 7 7 7 13 25 7 0 0 0 0 0 7 38 0 % R
% Ser: 0 0 7 0 0 7 0 25 0 7 7 7 7 7 7 % S
% Thr: 0 7 7 0 0 0 0 0 0 0 7 0 0 7 0 % T
% Val: 0 0 0 0 0 13 13 0 19 7 7 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 7 7 0 7 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _