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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC4
All Species:
23.64
Human Site:
S74
Identified Species:
34.67
UniProt:
O95801
Number Species:
15
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95801
NP_004614.3
387
44679
S74
I
I
F
D
E
E
R
S
P
E
E
Q
A
K
T
Chimpanzee
Pan troglodytes
XP_001153260
387
44743
S74
I
I
F
D
E
E
R
S
P
E
E
Q
A
K
T
Rhesus Macaque
Macaca mulatta
XP_001114145
387
44737
S74
I
I
F
D
E
E
R
S
P
E
E
Q
A
K
T
Dog
Lupus familis
XP_853176
358
40916
A95
V
L
Y
T
N
R
A
A
A
Q
Y
Y
L
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3H9
386
44320
Y74
M
I
F
D
D
D
R
Y
P
E
E
Q
A
K
T
Rat
Rattus norvegicus
NP_001013232
237
27309
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519382
216
24029
Chicken
Gallus gallus
XP_426665
313
35720
M69
E
P
A
E
L
A
A
M
Y
K
N
E
G
N
A
Frog
Xenopus laevis
NP_001085211
384
44859
E72
I
L
F
D
G
D
P
E
E
Q
A
K
S
Y
K
Zebra Danio
Brachydanio rerio
NP_001002122
402
46052
T74
I
I
H
D
D
D
R
T
P
E
E
K
A
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_525106
396
46888
T86
K
Y
D
P
E
E
N
T
R
D
E
L
A
L
N
Honey Bee
Apis mellifera
XP_624121
332
39077
T87
K
Y
G
E
D
E
N
T
P
E
E
L
A
N
N
Nematode Worm
Caenorhab. elegans
NP_495087
419
49032
D90
Y
D
K
E
D
D
E
D
K
Q
M
N
A
E
H
Sea Urchin
Strong. purpuratus
XP_791465
364
41863
T80
K
F
A
S
E
E
S
T
R
E
D
D
A
L
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P33313
385
44094
E78
K
A
L
A
Y
E
G
E
P
H
E
I
A
E
N
Red Bread Mold
Neurospora crassa
P23231
624
69413
E131
V
V
R
L
S
E
D
E
R
K
A
Y
A
A
K
Conservation
Percent
Protein Identity:
100
98.1
97.1
80.8
N.A.
82.4
53.2
N.A.
32
50.9
59.6
57.4
N.A.
31.3
36.6
30.7
42.1
Protein Similarity:
100
98.7
98.7
87.8
N.A.
90.4
57.8
N.A.
40
64.3
76.7
74.1
N.A.
51
55
47.9
61.5
P-Site Identity:
100
100
100
0
N.A.
73.3
0
N.A.
0
0
20
53.3
N.A.
26.6
33.3
6.6
26.6
P-Site Similarity:
100
100
100
33.3
N.A.
93.3
0
N.A.
0
20
53.3
93.3
N.A.
40
53.3
40
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.7
20.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.9
34.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
13
7
0
7
13
7
7
0
13
0
69
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
38
25
25
7
7
0
7
7
7
0
0
0
% D
% Glu:
7
0
0
19
32
50
7
19
7
44
50
7
0
13
0
% E
% Phe:
0
7
32
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
7
0
7
0
0
0
0
0
7
7
0
% G
% His:
0
0
7
0
0
0
0
0
0
7
0
0
0
0
7
% H
% Ile:
32
32
0
0
0
0
0
0
0
0
0
7
0
0
0
% I
% Lys:
25
0
7
0
0
0
0
0
7
13
0
13
0
25
13
% K
% Leu:
0
13
7
7
7
0
0
0
0
0
0
13
7
13
0
% L
% Met:
7
0
0
0
0
0
0
7
0
0
7
0
0
0
7
% M
% Asn:
0
0
0
0
7
0
13
0
0
0
7
7
0
13
25
% N
% Pro:
0
7
0
7
0
0
7
0
44
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
19
0
25
0
0
0
% Q
% Arg:
0
0
7
0
0
7
32
0
19
0
0
0
0
7
0
% R
% Ser:
0
0
0
7
7
0
7
19
0
0
0
0
7
0
7
% S
% Thr:
0
0
0
7
0
0
0
25
0
0
0
0
0
0
25
% T
% Val:
13
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
13
7
0
7
0
0
7
7
0
7
13
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _