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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC4
All Species:
19.09
Human Site:
T258
Identified Species:
28
UniProt:
O95801
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95801
NP_004614.3
387
44679
T258
L
F
L
D
G
L
S
T
E
N
P
H
G
A
R
Chimpanzee
Pan troglodytes
XP_001153260
387
44743
T258
L
F
L
D
G
L
S
T
E
N
P
H
G
A
R
Rhesus Macaque
Macaca mulatta
XP_001114145
387
44737
S258
L
F
L
D
G
L
S
S
E
N
P
H
G
A
R
Dog
Lupus familis
XP_853176
358
40916
S229
I
F
L
D
G
L
S
S
D
N
P
Y
G
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3H9
386
44320
Q224
H
Q
N
E
A
L
L
Q
A
I
K
A
R
N
I
Rat
Rattus norvegicus
NP_001013232
237
27309
K109
Y
S
E
G
L
K
K
K
C
A
D
P
D
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519382
216
24029
L88
Q
E
R
D
I
K
L
L
P
L
A
A
G
E
K
Chicken
Gallus gallus
XP_426665
313
35720
A182
L
L
E
A
R
A
K
A
D
K
L
K
E
R
N
Frog
Xenopus laevis
NP_001085211
384
44859
S253
L
P
F
D
A
V
S
S
E
N
A
T
G
A
Q
Zebra Danio
Brachydanio rerio
NP_001002122
402
46052
Q270
Q
L
D
G
I
S
S
Q
E
A
T
G
A
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_525106
396
46888
L266
E
L
L
Y
P
K
F
L
P
L
E
D
H
P
V
Honey Bee
Apis mellifera
XP_624121
332
39077
T196
Q
L
L
D
E
S
P
T
D
K
I
I
L
H
L
Nematode Worm
Caenorhab. elegans
NP_495087
419
49032
P288
A
R
L
T
V
S
L
P
L
M
H
S
H
E
C
Sea Urchin
Strong. purpuratus
XP_791465
364
41863
T234
K
L
I
A
A
L
K
T
R
N
L
R
F
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P33313
385
44094
G251
P
V
E
L
L
N
E
G
K
I
R
L
E
D
P
Red Bread Mold
Neurospora crassa
P23231
624
69413
E394
L
G
H
P
D
K
A
E
E
D
F
N
K
A
I
Conservation
Percent
Protein Identity:
100
98.1
97.1
80.8
N.A.
82.4
53.2
N.A.
32
50.9
59.6
57.4
N.A.
31.3
36.6
30.7
42.1
Protein Similarity:
100
98.7
98.7
87.8
N.A.
90.4
57.8
N.A.
40
64.3
76.7
74.1
N.A.
51
55
47.9
61.5
P-Site Identity:
100
100
93.3
73.3
N.A.
6.6
0
N.A.
13.3
6.6
46.6
13.3
N.A.
6.6
20
6.6
20
P-Site Similarity:
100
100
100
100
N.A.
13.3
0
N.A.
20
13.3
66.6
13.3
N.A.
6.6
26.6
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.7
20.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.9
34.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
13
19
7
7
7
7
13
13
13
7
38
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
7
% C
% Asp:
0
0
7
44
7
0
0
0
19
7
7
7
7
7
0
% D
% Glu:
7
7
19
7
7
0
7
7
38
0
7
0
13
13
0
% E
% Phe:
0
25
7
0
0
0
7
0
0
0
7
0
7
0
0
% F
% Gly:
0
7
0
13
25
0
0
7
0
0
0
7
38
0
0
% G
% His:
7
0
7
0
0
0
0
0
0
0
7
19
13
7
0
% H
% Ile:
7
0
7
0
13
0
0
0
0
13
7
7
0
0
13
% I
% Lys:
7
0
0
0
0
25
19
7
7
13
7
7
7
0
7
% K
% Leu:
38
32
44
7
13
38
19
13
7
13
13
7
7
13
7
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
7
0
0
0
38
0
7
0
7
13
% N
% Pro:
7
7
0
7
7
0
7
7
13
0
25
7
0
7
7
% P
% Gln:
19
7
0
0
0
0
0
13
0
0
0
0
0
0
7
% Q
% Arg:
0
7
7
0
7
0
0
0
7
0
7
7
7
13
25
% R
% Ser:
0
7
0
0
0
19
38
19
0
0
0
7
0
0
7
% S
% Thr:
0
0
0
7
0
0
0
25
0
0
7
7
0
0
0
% T
% Val:
0
7
0
0
7
7
0
0
0
0
0
0
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
7
0
0
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _