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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC4
All Species:
39.09
Human Site:
Y120
Identified Species:
57.33
UniProt:
O95801
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95801
NP_004614.3
387
44679
Y120
P
D
L
N
A
V
L
Y
T
N
R
A
A
A
Q
Chimpanzee
Pan troglodytes
XP_001153260
387
44743
Y120
P
D
L
N
A
V
L
Y
T
N
R
A
A
A
Q
Rhesus Macaque
Macaca mulatta
XP_001114145
387
44737
Y120
P
D
L
N
A
V
L
Y
T
N
R
A
A
A
Q
Dog
Lupus familis
XP_853176
358
40916
Q149
N
W
C
D
E
G
L
Q
I
D
A
R
E
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3H9
386
44320
Y120
P
D
L
N
A
V
L
Y
T
N
R
A
A
A
Q
Rat
Rattus norvegicus
NP_001013232
237
27309
A49
I
P
L
F
M
K
K
A
P
S
E
I
D
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519382
216
24029
Q28
H
P
D
L
A
C
L
Q
S
M
I
F
D
D
E
Chicken
Gallus gallus
XP_426665
313
35720
G119
A
A
A
Q
C
R
L
G
N
Y
R
S
A
L
A
Frog
Xenopus laevis
NP_001085211
384
44859
Y116
Q
E
L
N
A
I
L
Y
T
N
R
A
A
A
Q
Zebra Danio
Brachydanio rerio
NP_001002122
402
46052
Y120
P
E
L
N
A
V
L
Y
T
N
R
A
A
A
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_525106
396
46888
Y132
P
D
V
L
A
V
L
Y
N
N
R
S
A
A
H
Honey Bee
Apis mellifera
XP_624121
332
39077
Y133
V
D
L
M
A
Q
L
Y
N
N
R
A
A
A
H
Nematode Worm
Caenorhab. elegans
NP_495087
419
49032
Y136
R
K
L
N
A
V
L
Y
F
N
R
A
A
A
Q
Sea Urchin
Strong. purpuratus
XP_791465
364
41863
Y126
K
D
I
N
A
V
L
Y
T
N
R
A
A
A
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P33313
385
44094
Y124
K
S
I
N
E
S
L
Y
A
N
R
A
A
C
E
Red Bread Mold
Neurospora crassa
P23231
624
69413
L206
D
P
H
Y
V
K
A
L
N
R
R
A
N
A
Y
Conservation
Percent
Protein Identity:
100
98.1
97.1
80.8
N.A.
82.4
53.2
N.A.
32
50.9
59.6
57.4
N.A.
31.3
36.6
30.7
42.1
Protein Similarity:
100
98.7
98.7
87.8
N.A.
90.4
57.8
N.A.
40
64.3
76.7
74.1
N.A.
51
55
47.9
61.5
P-Site Identity:
100
100
100
6.6
N.A.
100
6.6
N.A.
13.3
20
80
86.6
N.A.
66.6
66.6
80
80
P-Site Similarity:
100
100
100
26.6
N.A.
100
20
N.A.
26.6
26.6
93.3
93.3
N.A.
80
66.6
80
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.7
20.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.9
34.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
0
69
0
7
7
7
0
7
69
75
69
7
% A
% Cys:
0
0
7
0
7
7
0
0
0
0
0
0
0
7
0
% C
% Asp:
7
44
7
7
0
0
0
0
0
7
0
0
13
7
0
% D
% Glu:
0
13
0
0
13
0
0
0
0
0
7
0
7
0
13
% E
% Phe:
0
0
0
7
0
0
0
0
7
0
0
7
0
0
0
% F
% Gly:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% G
% His:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
25
% H
% Ile:
7
0
13
0
0
7
0
0
7
0
7
7
0
0
0
% I
% Lys:
13
7
0
0
0
13
7
0
0
0
0
0
0
7
13
% K
% Leu:
0
0
57
13
0
0
88
7
0
0
0
0
0
7
0
% L
% Met:
0
0
0
7
7
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
7
0
0
57
0
0
0
0
25
69
0
0
7
0
0
% N
% Pro:
38
19
0
0
0
0
0
0
7
0
0
0
0
7
0
% P
% Gln:
7
0
0
7
0
7
0
13
0
0
0
0
0
0
38
% Q
% Arg:
7
0
0
0
0
7
0
0
0
7
82
7
0
0
0
% R
% Ser:
0
7
0
0
0
7
0
0
7
7
0
13
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
44
0
0
0
0
0
0
% T
% Val:
7
0
7
0
7
50
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
69
0
7
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _