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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC4
All Species:
16.97
Human Site:
Y355
Identified Species:
24.89
UniProt:
O95801
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95801
NP_004614.3
387
44679
Y355
Q
V
L
Q
H
Q
R
Y
F
V
K
A
L
T
P
Chimpanzee
Pan troglodytes
XP_001153260
387
44743
Y355
Q
V
L
Q
H
Q
R
Y
F
V
K
A
L
T
P
Rhesus Macaque
Macaca mulatta
XP_001114145
387
44737
Y355
Q
V
L
Q
H
H
R
Y
F
V
K
A
L
T
P
Dog
Lupus familis
XP_853176
358
40916
Y326
Q
V
L
Q
H
P
R
Y
L
V
K
A
L
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3H9
386
44320
Y321
S
W
D
S
E
H
K
Y
H
P
E
N
L
E
V
Rat
Rattus norvegicus
NP_001013232
237
27309
R206
R
M
E
E
R
D
L
R
K
A
K
L
K
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519382
216
24029
P185
L
E
V
R
G
V
H
P
P
R
G
L
V
G
R
Chicken
Gallus gallus
XP_426665
313
35720
Y279
P
W
D
L
E
R
K
Y
L
P
S
N
L
E
L
Frog
Xenopus laevis
NP_001085211
384
44859
F350
E
A
M
Q
H
R
R
F
R
V
K
A
G
T
P
Zebra Danio
Brachydanio rerio
NP_001002122
402
46052
C367
R
V
L
Q
H
Q
R
C
S
V
K
A
G
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_525106
396
46888
F363
E
I
I
A
E
K
G
F
F
V
S
G
G
A
L
Honey Bee
Apis mellifera
XP_624121
332
39077
I293
C
S
L
H
K
V
D
I
G
Q
S
L
G
K
I
Nematode Worm
Caenorhab. elegans
NP_495087
419
49032
Y385
S
V
L
S
M
P
G
Y
Q
I
K
Q
G
L
P
Sea Urchin
Strong. purpuratus
XP_791465
364
41863
Q331
W
D
P
E
R
K
Y
Q
V
K
N
L
K
V
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P33313
385
44094
P348
D
I
L
K
K
E
S
P
D
V
P
L
F
D
N
Red Bread Mold
Neurospora crassa
P23231
624
69413
K491
E
L
L
L
D
Q
N
K
F
Q
E
A
I
E
K
Conservation
Percent
Protein Identity:
100
98.1
97.1
80.8
N.A.
82.4
53.2
N.A.
32
50.9
59.6
57.4
N.A.
31.3
36.6
30.7
42.1
Protein Similarity:
100
98.7
98.7
87.8
N.A.
90.4
57.8
N.A.
40
64.3
76.7
74.1
N.A.
51
55
47.9
61.5
P-Site Identity:
100
100
93.3
86.6
N.A.
13.3
6.6
N.A.
0
13.3
53.3
73.3
N.A.
13.3
6.6
33.3
0
P-Site Similarity:
100
100
93.3
86.6
N.A.
26.6
26.6
N.A.
20
26.6
80
80
N.A.
46.6
6.6
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.7
20.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.9
34.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
0
0
0
0
0
7
0
44
0
7
0
% A
% Cys:
7
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
7
7
13
0
7
7
7
0
7
0
0
0
0
7
0
% D
% Glu:
19
7
7
13
19
7
0
0
0
0
13
0
0
25
0
% E
% Phe:
0
0
0
0
0
0
0
13
32
0
0
0
7
0
0
% F
% Gly:
0
0
0
0
7
0
13
0
7
0
7
7
32
7
0
% G
% His:
0
0
0
7
38
13
7
0
7
0
0
0
0
0
0
% H
% Ile:
0
13
7
0
0
0
0
7
0
7
0
0
7
0
7
% I
% Lys:
0
0
0
7
13
13
13
7
7
7
50
0
13
7
13
% K
% Leu:
7
7
57
13
0
0
7
0
13
0
0
32
38
7
13
% L
% Met:
0
7
7
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
0
0
0
7
13
0
0
7
% N
% Pro:
7
0
7
0
0
13
0
13
7
13
7
0
0
0
44
% P
% Gln:
25
0
0
38
0
25
0
7
7
13
0
7
0
0
0
% Q
% Arg:
13
0
0
7
13
13
38
7
7
7
0
0
0
0
7
% R
% Ser:
13
7
0
13
0
0
7
0
7
0
19
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
38
0
% T
% Val:
0
38
7
0
0
13
0
0
7
50
0
0
7
7
7
% V
% Trp:
7
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
44
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _