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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM50A
All Species:
27.27
Human Site:
T22
Identified Species:
50
UniProt:
O95807
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95807
NP_055128.1
157
17400
T22
D
W
G
E
K
R
N
T
I
A
S
I
A
A
G
Chimpanzee
Pan troglodytes
XP_001137896
126
13977
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535354
157
17353
T22
D
W
G
E
K
R
N
T
I
A
S
V
A
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXL1
157
17477
T22
D
W
G
E
K
R
N
T
I
A
S
I
A
A
G
Rat
Rattus norvegicus
NP_001120997
157
17375
T22
D
W
G
E
K
R
N
T
V
A
S
I
A
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510935
157
17397
T22
D
W
G
E
K
R
N
T
I
A
S
V
A
A
G
Chicken
Gallus gallus
XP_001232925
196
21690
K61
A
E
A
L
R
A
L
K
D
V
R
F
P
G
E
Frog
Xenopus laevis
NP_001089470
157
17318
T22
D
W
G
E
K
R
N
T
V
A
S
V
A
A
G
Zebra Danio
Brachydanio rerio
NP_998694
164
18145
T25
D
W
G
E
K
R
N
T
I
A
S
I
A
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647888
152
16919
I23
S
R
N
R
N
T
S
I
I
A
G
L
L
F
F
Honey Bee
Apis mellifera
XP_624182
155
17167
R22
W
F
E
I
G
N
K
R
N
V
L
V
S
M
F
Nematode Worm
Caenorhab. elegans
NP_490985
157
17388
A22
D
L
E
G
R
R
N
A
V
A
S
V
V
S
A
Sea Urchin
Strong. purpuratus
XP_783010
165
18104
F25
A
I
P
E
K
R
N
F
I
S
S
I
A
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.2
N.A.
96.8
N.A.
94.2
94.2
N.A.
93.6
65.8
86.6
84.7
N.A.
37.5
49.6
44.5
65.4
Protein Similarity:
100
80.2
N.A.
99.3
N.A.
96.8
97.4
N.A.
97.4
72.9
93.6
91.4
N.A.
55.4
66.8
64.9
77.5
P-Site Identity:
100
0
N.A.
93.3
N.A.
100
93.3
N.A.
93.3
0
86.6
100
N.A.
13.3
0
33.3
66.6
P-Site Similarity:
100
0
N.A.
100
N.A.
100
100
N.A.
100
6.6
100
100
N.A.
26.6
20
60
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
8
0
0
8
0
8
0
70
0
0
62
62
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
62
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
8
16
62
0
0
0
0
0
0
0
0
0
0
8
% E
% Phe:
0
8
0
0
0
0
0
8
0
0
0
8
0
8
16
% F
% Gly:
0
0
54
8
8
0
0
0
0
0
8
0
0
8
62
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
8
0
0
0
8
54
0
0
39
0
0
0
% I
% Lys:
0
0
0
0
62
0
8
8
0
0
0
0
0
0
0
% K
% Leu:
0
8
0
8
0
0
8
0
0
0
8
8
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
8
0
8
8
70
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
8
16
70
0
8
0
0
8
0
0
0
0
% R
% Ser:
8
0
0
0
0
0
8
0
0
8
70
0
8
8
0
% S
% Thr:
0
0
0
0
0
8
0
54
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
24
16
0
39
8
0
0
% V
% Trp:
8
54
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _