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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SDPR All Species: 13.33
Human Site: S192 Identified Species: 32.59
UniProt: O95810 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95810 NP_004648.1 425 47173 S192 E L P D E N K S L E E T L H T
Chimpanzee Pan troglodytes XP_001167854 425 47228 S192 E L P D E N K S L E E T L H T
Rhesus Macaque Macaca mulatta XP_001084498 425 47255 S192 E L P D E N K S L E E T L H T
Dog Lupus familis XP_545572 543 59322 S310 E L A E D N Q S L E E T L H T
Cat Felis silvestris
Mouse Mus musculus Q63918 418 46745 G182 P V P S A A E G K E E L A D E
Rat Rattus norvegicus Q66H98 417 46368 E181 E P V P S T A E G K E L A D E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513924 343 39493 L112 A R V E K Q N L N V R K V E A
Chicken Gallus gallus XP_421903 392 43358 K160 E E P V D E N K T L E E T L H
Frog Xenopus laevis A2VDA9 359 41001 N128 Q E E M L R K N K F R V V I F
Zebra Danio Brachydanio rerio A1L260 329 36516 V98 V K E V R S R V E K Q N V R V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 96 43.6 N.A. 82.8 82.1 N.A. 26.5 56.2 28 30.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 97.8 56.5 N.A. 88 88.2 N.A. 49.8 69.8 52.9 49.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 73.3 N.A. 20 13.3 N.A. 0 20 6.6 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 33.3 20 N.A. 20 26.6 26.6 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 10 10 10 0 0 0 0 0 20 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 30 20 0 0 0 0 0 0 0 0 20 0 % D
% Glu: 60 20 20 20 30 10 10 10 10 50 70 10 0 10 20 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % F
% Gly: 0 0 0 0 0 0 0 10 10 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 40 10 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 10 0 0 10 0 40 10 20 20 0 10 0 0 0 % K
% Leu: 0 40 0 0 10 0 0 10 40 10 0 20 40 10 0 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 40 20 10 10 0 0 10 0 0 0 % N
% Pro: 10 10 50 10 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 10 10 0 0 0 10 0 0 0 0 % Q
% Arg: 0 10 0 0 10 10 10 0 0 0 20 0 0 10 0 % R
% Ser: 0 0 0 10 10 10 0 40 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 10 0 0 10 0 0 40 10 0 40 % T
% Val: 10 10 20 20 0 0 0 10 0 10 0 10 30 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _