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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDPR
All Species:
16.67
Human Site:
S218
Identified Species:
40.74
UniProt:
O95810
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95810
NP_004648.1
425
47173
S218
D
E
E
A
L
E
D
S
A
E
E
K
V
E
E
Chimpanzee
Pan troglodytes
XP_001167854
425
47228
S218
D
E
E
A
L
E
D
S
A
E
E
K
V
E
E
Rhesus Macaque
Macaca mulatta
XP_001084498
425
47255
S218
D
E
E
A
L
E
D
S
A
E
E
K
V
E
E
Dog
Lupus familis
XP_545572
543
59322
S336
D
E
E
A
L
Q
D
S
S
E
E
A
M
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q63918
418
46745
L208
D
L
S
S
D
D
E
L
P
R
D
E
E
A
L
Rat
Rattus norvegicus
Q66H98
417
46368
L207
D
L
S
S
D
D
E
L
P
G
D
E
E
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513924
343
39493
E138
R
V
V
V
F
Q
E
E
M
Q
C
P
T
S
L
Chicken
Gallus gallus
XP_421903
392
43358
S186
H
E
D
D
V
G
D
S
A
D
E
K
A
E
E
Frog
Xenopus laevis
A2VDA9
359
41001
D154
V
A
K
Q
S
A
L
D
G
N
L
R
D
D
L
Zebra Danio
Brachydanio rerio
A1L260
329
36516
V124
T
R
N
K
F
R
V
V
I
Y
Q
G
E
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96
43.6
N.A.
82.8
82.1
N.A.
26.5
56.2
28
30.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
97.8
56.5
N.A.
88
88.2
N.A.
49.8
69.8
52.9
49.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
6.6
6.6
N.A.
0
53.3
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
40
40
N.A.
20
73.3
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
40
0
10
0
0
40
0
0
10
10
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
60
0
10
10
20
20
50
10
0
10
20
0
10
10
0
% D
% Glu:
0
50
40
0
0
30
30
10
0
40
50
20
30
50
60
% E
% Phe:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
10
10
0
10
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
10
10
0
0
0
0
0
0
0
40
0
10
0
% K
% Leu:
0
20
0
0
40
0
10
20
0
0
10
0
0
0
40
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
20
0
0
10
0
0
0
% P
% Gln:
0
0
0
10
0
20
0
0
0
10
10
0
0
0
0
% Q
% Arg:
10
10
0
0
0
10
0
0
0
10
0
10
0
0
0
% R
% Ser:
0
0
20
20
10
0
0
50
10
0
0
0
0
10
0
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
10
10
10
10
10
0
10
10
0
0
0
0
30
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _