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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CER1 All Species: 17.58
Human Site: S29 Identified Species: 38.67
UniProt: O95813 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95813 NP_005445.1 267 30084 S29 D G R Q N Q S S L S P V L L P
Chimpanzee Pan troglodytes XP_528542 267 30099 S29 D G R Q N Q S S L S P V L L P
Rhesus Macaque Macaca mulatta XP_001110846 267 30242 S29 D G R Q N Q N S L S P A L L P
Dog Lupus familis XP_853753 270 30424 S29 D G R Q T Q S S V S P V I L E
Cat Felis silvestris
Mouse Mus musculus O55233 272 30413 S29 D G C Q S Q G S L S F P L L E
Rat Rattus norvegicus O35793 184 20661
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515212 238 25907 C19 V L W G T Q A C S R T S E L P
Chicken Gallus gallus Q9PWB0 272 31206 R29 D S Q Q R K R R P L Q H L F Y
Frog Xenopus laevis P70041 270 30705 T31 E G R E R T K T Y S L N S R G
Zebra Danio Brachydanio rerio NP_998134 243 27055 A23 I G A F P R N A F Q R E F H R
Tiger Blowfish Takifugu rubipres NP_001027911 255 27111 H23 A L A F T L P H S A F D F L K
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.1 94.3 78.5 N.A. 67.2 24.7 N.A. 24.7 43 27.4 23.6 28.8 N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.8 95.5 84.4 N.A. 76.8 37 N.A. 37.8 55.5 47 42.3 41.2 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 73.3 N.A. 60 0 N.A. 20 20 20 6.6 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 86.6 N.A. 66.6 0 N.A. 26.6 33.3 40 26.6 13.3 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 19 0 0 0 10 10 0 10 0 10 0 0 0 % A
% Cys: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 55 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 10 0 0 10 0 0 0 0 0 0 0 10 10 0 19 % E
% Phe: 0 0 0 19 0 0 0 0 10 0 19 0 19 10 0 % F
% Gly: 0 64 0 10 0 0 10 0 0 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 10 0 10 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % I
% Lys: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 10 % K
% Leu: 0 19 0 0 0 10 0 0 37 10 10 0 46 64 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 28 0 19 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 0 0 10 0 10 0 10 0 37 10 0 0 37 % P
% Gln: 0 0 10 55 0 55 0 0 0 10 10 0 0 0 0 % Q
% Arg: 0 0 46 0 19 10 10 10 0 10 10 0 0 10 10 % R
% Ser: 0 10 0 0 10 0 28 46 19 55 0 10 10 0 0 % S
% Thr: 0 0 0 0 28 10 0 10 0 0 10 0 0 0 0 % T
% Val: 10 0 0 0 0 0 0 0 10 0 0 28 0 0 0 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _