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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLYCD
All Species:
33.03
Human Site:
S387
Identified Species:
55.9
UniProt:
O95822
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95822
NP_036345.2
493
55003
S387
S
S
S
E
W
V
Q
S
E
K
L
V
R
A
L
Chimpanzee
Pan troglodytes
XP_523518
493
54957
S387
S
S
S
E
W
V
Q
S
E
K
L
A
R
A
L
Rhesus Macaque
Macaca mulatta
XP_001112117
493
54893
S387
G
S
S
E
W
V
Q
S
E
T
L
V
R
A
L
Dog
Lupus familis
XP_852152
442
48705
S336
S
S
S
E
W
I
K
S
E
K
L
V
R
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99J39
492
54718
S386
S
S
G
E
W
V
K
S
E
K
L
T
Q
A
L
Rat
Rattus norvegicus
Q920F5
492
54744
S386
S
S
G
E
W
A
K
S
E
K
L
A
Q
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508710
449
50992
S343
T
S
N
E
W
V
K
S
E
K
L
V
K
V
L
Chicken
Gallus gallus
XP_414174
547
60873
S441
N
N
N
E
W
V
R
S
E
K
L
V
N
A
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001082972
504
57530
S398
S
T
S
E
W
I
H
S
D
R
L
V
R
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625201
377
44289
K283
K
I
S
E
V
L
K
K
P
L
L
R
A
C
A
Nematode Worm
Caenorhab. elegans
NP_001022561
442
50154
K345
V
I
S
N
E
K
T
K
K
E
Q
L
N
A
I
Sea Urchin
Strong. purpuratus
XP_001184115
408
46014
N314
D
S
F
K
S
A
L
N
I
T
S
L
Q
A
L
Poplar Tree
Populus trichocarpa
XP_002331555
468
52961
A337
N
S
A
L
E
T
Y
A
G
K
N
G
M
E
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_192341
518
58433
G400
L
S
D
E
S
S
S
G
S
N
G
M
E
V
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.5
74.8
N.A.
88
88.2
N.A.
67.7
65
N.A.
58.3
N.A.
N.A.
39.7
34.8
41.7
Protein Similarity:
100
98.9
97.3
80.7
N.A.
91.8
92.4
N.A.
76.2
75.5
N.A.
71.6
N.A.
N.A.
53.9
51.3
54.9
P-Site Identity:
100
93.3
86.6
86.6
N.A.
73.3
66.6
N.A.
66.6
66.6
N.A.
66.6
N.A.
N.A.
20
13.3
20
P-Site Similarity:
100
93.3
86.6
100
N.A.
86.6
80
N.A.
93.3
93.3
N.A.
93.3
N.A.
N.A.
33.3
40
46.6
Percent
Protein Identity:
38.1
N.A.
N.A.
37.4
N.A.
N.A.
Protein Similarity:
54.1
N.A.
N.A.
53.8
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
15
0
8
0
0
0
15
8
72
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
8
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
79
15
0
0
0
58
8
0
0
8
8
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
15
0
0
0
0
8
8
0
8
8
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
15
0
0
0
15
0
0
8
0
0
0
0
0
8
% I
% Lys:
8
0
0
8
0
8
36
15
8
58
0
0
8
0
0
% K
% Leu:
8
0
0
8
0
8
8
0
0
8
72
15
0
0
79
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% M
% Asn:
15
8
15
8
0
0
0
8
0
8
8
0
15
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
22
0
0
0
8
0
22
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
8
0
8
36
0
0
% R
% Ser:
43
72
50
0
15
8
8
65
8
0
8
0
0
0
0
% S
% Thr:
8
8
0
0
0
8
8
0
0
15
0
8
0
0
0
% T
% Val:
8
0
0
0
8
43
0
0
0
0
0
43
0
15
8
% V
% Trp:
0
0
0
0
65
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _