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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLYCD
All Species:
15.15
Human Site:
T346
Identified Species:
25.64
UniProt:
O95822
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95822
NP_036345.2
493
55003
T346
L
G
L
L
N
S
Q
T
K
E
H
G
R
N
E
Chimpanzee
Pan troglodytes
XP_523518
493
54957
M346
L
G
L
L
N
S
Q
M
K
E
H
G
R
N
E
Rhesus Macaque
Macaca mulatta
XP_001112117
493
54893
V346
L
G
L
L
N
S
Q
V
K
D
H
G
R
N
E
Dog
Lupus familis
XP_852152
442
48705
G295
L
G
L
L
S
S
Q
G
K
E
H
G
R
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99J39
492
54718
G345
L
G
L
L
N
V
Q
G
K
E
H
G
R
N
E
Rat
Rattus norvegicus
Q920F5
492
54744
G345
L
G
L
L
N
V
Q
G
K
E
Y
G
R
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508710
449
50992
T302
L
G
N
L
S
S
Q
T
K
E
L
G
R
N
E
Chicken
Gallus gallus
XP_414174
547
60873
T400
V
G
L
L
S
S
Q
T
K
E
L
E
K
N
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001082972
504
57530
R357
G
Q
H
K
K
E
G
R
A
T
E
L
L
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625201
377
44289
T242
Q
D
I
Y
N
I
F
T
N
E
E
C
N
S
I
Nematode Worm
Caenorhab. elegans
NP_001022561
442
50154
S304
I
R
N
L
K
G
N
S
E
Y
P
S
I
M
N
Sea Urchin
Strong. purpuratus
XP_001184115
408
46014
S273
P
S
M
H
L
F
S
S
L
S
P
I
P
G
F
Poplar Tree
Populus trichocarpa
XP_002331555
468
52961
S296
L
S
K
L
A
S
Q
S
V
I
A
K
V
D
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_192341
518
58433
S359
L
S
K
L
S
S
Q
S
R
F
A
E
D
E
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.5
74.8
N.A.
88
88.2
N.A.
67.7
65
N.A.
58.3
N.A.
N.A.
39.7
34.8
41.7
Protein Similarity:
100
98.9
97.3
80.7
N.A.
91.8
92.4
N.A.
76.2
75.5
N.A.
71.6
N.A.
N.A.
53.9
51.3
54.9
P-Site Identity:
100
93.3
86.6
80
N.A.
86.6
80
N.A.
80
66.6
N.A.
6.6
N.A.
N.A.
20
6.6
0
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
86.6
86.6
N.A.
86.6
86.6
N.A.
13.3
N.A.
N.A.
33.3
26.6
13.3
Percent
Protein Identity:
38.1
N.A.
N.A.
37.4
N.A.
N.A.
Protein Similarity:
54.1
N.A.
N.A.
53.8
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
8
0
15
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
8
0
0
8
8
0
% D
% Glu:
0
0
0
0
0
8
0
0
8
58
15
15
0
8
65
% E
% Phe:
0
0
0
0
0
8
8
0
0
8
0
0
0
0
8
% F
% Gly:
8
58
0
0
0
8
8
22
0
0
0
50
0
8
0
% G
% His:
0
0
8
8
0
0
0
0
0
0
36
0
0
0
0
% H
% Ile:
8
0
8
0
0
8
0
0
0
8
0
8
8
0
8
% I
% Lys:
0
0
15
8
15
0
0
0
58
0
0
8
8
0
0
% K
% Leu:
65
0
50
79
8
0
0
0
8
0
15
8
8
0
0
% L
% Met:
0
0
8
0
0
0
0
8
0
0
0
0
0
8
0
% M
% Asn:
0
0
15
0
43
0
8
0
8
0
0
0
8
50
15
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
15
0
8
0
0
% P
% Gln:
8
8
0
0
0
0
72
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
8
8
0
0
0
50
0
8
% R
% Ser:
0
22
0
0
29
58
8
29
0
8
0
8
0
22
0
% S
% Thr:
0
0
0
0
0
0
0
29
0
8
0
0
0
0
0
% T
% Val:
8
0
0
0
0
15
0
8
8
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _