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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MLYCD All Species: 20.3
Human Site: T51 Identified Species: 34.36
UniProt: O95822 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95822 NP_036345.2 493 55003 T51 L R R A V P P T P A Y E L R E
Chimpanzee Pan troglodytes XP_523518 493 54957 T51 L R R A V P P T P A Y E L R E
Rhesus Macaque Macaca mulatta XP_001112117 493 54893 T51 L R R A V P P T P A Y E L R E
Dog Lupus familis XP_852152 442 48705 E41 S F Y G G L A E A A E R A D L
Cat Felis silvestris
Mouse Mus musculus Q99J39 492 54718 T50 L R R A V P P T P A Y E L R E
Rat Rattus norvegicus Q920F5 492 54744 T50 L R R A V P P T P A Y E L R E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508710 449 50992 P41 L R G A E H C P E R F G M E K
Chicken Gallus gallus XP_414174 547 60873 L105 L S R S V P P L P P Y E T K E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001082972 504 57530 L60 L R K T V A P L P S Y E M R D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_625201 377 44289
Nematode Worm Caenorhab. elegans NP_001022561 442 50154 S47 F S K L Y A N S T P E T R K S
Sea Urchin Strong. purpuratus XP_001184115 408 46014 G36 S A V A S G M G V R H D K I L
Poplar Tree Populus trichocarpa XP_002331555 468 52961 L45 V L A K E Y D L N R I Q V R E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_192341 518 58433 T64 V Y D V V R E T M H S A I S A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 96.5 74.8 N.A. 88 88.2 N.A. 67.7 65 N.A. 58.3 N.A. N.A. 39.7 34.8 41.7
Protein Similarity: 100 98.9 97.3 80.7 N.A. 91.8 92.4 N.A. 76.2 75.5 N.A. 71.6 N.A. N.A. 53.9 51.3 54.9
P-Site Identity: 100 100 100 6.6 N.A. 100 100 N.A. 20 60 N.A. 53.3 N.A. N.A. 0 0 6.6
P-Site Similarity: 100 100 100 6.6 N.A. 100 100 N.A. 40 73.3 N.A. 80 N.A. N.A. 0 20 20
Percent
Protein Identity: 38.1 N.A. N.A. 37.4 N.A. N.A.
Protein Similarity: 54.1 N.A. N.A. 53.8 N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 33.3 N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 50 0 15 8 0 8 43 0 8 8 0 8 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 8 0 0 0 0 8 0 8 8 % D
% Glu: 0 0 0 0 15 0 8 8 8 0 15 50 0 8 50 % E
% Phe: 8 8 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 0 8 8 8 8 0 8 0 0 0 8 0 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 8 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 8 0 8 8 0 % I
% Lys: 0 0 15 8 0 0 0 0 0 0 0 0 8 15 8 % K
% Leu: 58 8 0 8 0 8 0 22 0 0 0 0 36 0 15 % L
% Met: 0 0 0 0 0 0 8 0 8 0 0 0 15 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 43 50 8 50 15 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Q
% Arg: 0 50 43 0 0 8 0 0 0 22 0 8 8 50 0 % R
% Ser: 15 15 0 8 8 0 0 8 0 8 8 0 0 8 8 % S
% Thr: 0 0 0 8 0 0 0 43 8 0 0 8 8 0 0 % T
% Val: 15 0 8 8 58 0 0 0 8 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 8 0 8 8 0 0 0 0 50 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _